A0A172Y9X6 · A0A172Y9X6_9GAMM

  • Protein
    Tyrosine--tRNA ligase
  • Gene
    tyrS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Catalytic activity

Features

Showing features for binding site.

140250100150200250300350400
TypeIDPosition(s)Description
Binding site229ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionRNA binding
Molecular Functiontyrosine-tRNA ligase activity
Biological Processtyrosyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine--tRNA ligase
  • EC number
  • Alternative names
    • Tyrosyl-tRNA synthetase
      (TyrRS
      )

Gene names

    • Name
      tyrS
    • ORF names
      A5892_00025

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • IHB B 13600
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Oceanospirillales > Halomonadaceae > Halotalea

Accessions

  • Primary accession
    A0A172Y9X6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif42-51'HIGH' region
Motif226-230'KMSKS' region

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    402
  • Mass (Da)
    44,665
  • Last updated
    2016-09-07 v1
  • Checksum
    B86BE8300B254AC6
MNDVVEAFELIKRGTDEILLEDALLEKLRSGRKLRIKVGFDPTAPDLHLGHSVLLTKMRQLQELGHTVIFLIGDFTGRIGDPSGKSVTRKPLTEEQVRANAETYRQQVFKILDPELTEVRFNSEWFSRMGAAEMIELAAQSTVARMLERDDFEKRYQANQAISLHEFLYPLVQGYDSVALEADIEMGGTDQKFNLLMGREIQKHFGQTPQVVITMPLLEGLDGVQKMSKSLGNYVGVDEAPGAMFNKLVSMPDALIWKYFDLLSLKSNAELEALREEMANGANPRDIKMVLARELIARYHGEEAAANAHRSSGNVLGDGELPEDMPEVEVAFSGDAGVPIGFVLNRSGLVKNSAQAKDLLNNGRVKVDGVVMDKDALLEFGRSYVVQAGKRSFARVSLVPER

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP015243
EMBL· GenBank· DDBJ
ANF56051.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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