A0A172RGX3 · A0A172RGX3_CANLF

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespirasome
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 6
  • EC number

Gene names

    • Name
      ND6

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • 100T
    • 179T1
    • 432T
    • 451T
    • 452T
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis

Accessions

  • Primary accession
    A0A172RGX3

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-22Helical
Transmembrane27-45Helical
Transmembrane51-76Helical
Transmembrane88-109Helical
Transmembrane146-169Helical

Keywords

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Sequence similarities

Belongs to the complex I subunit 6 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    175
  • Mass (Da)
    18,853
  • Last updated
    2016-09-07 v1
  • Checksum
    BEFEF13A8E74204E
MMTYIVFILSIVFVMSFVGFATKPSPIYGGLVLIISGGIGCAIVLNFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKAVLAAFVTGLLSELLTACYILKDDEVEVVLKFNGMGDWVIYDTGDSGFFSEEAVGIAALYSYGTWLVVVTGWSLLIGVLVIMEVTRGN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU290401
EMBL· GenBank· DDBJ
ANE11249.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290461
EMBL· GenBank· DDBJ
ANE12029.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290662
EMBL· GenBank· DDBJ
ANE14639.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290687
EMBL· GenBank· DDBJ
ANE14963.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290688
EMBL· GenBank· DDBJ
ANE14976.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290689
EMBL· GenBank· DDBJ
ANE14989.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290690
EMBL· GenBank· DDBJ
ANE15002.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290691
EMBL· GenBank· DDBJ
ANE15015.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290692
EMBL· GenBank· DDBJ
ANE15028.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290693
EMBL· GenBank· DDBJ
ANE15041.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290695
EMBL· GenBank· DDBJ
ANE15067.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290754
EMBL· GenBank· DDBJ
ANE15834.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290765
EMBL· GenBank· DDBJ
ANE15977.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290766
EMBL· GenBank· DDBJ
ANE15990.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290768
EMBL· GenBank· DDBJ
ANE16016.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290772
EMBL· GenBank· DDBJ
ANE16068.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290776
EMBL· GenBank· DDBJ
ANE16120.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290778
EMBL· GenBank· DDBJ
ANE16146.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290791
EMBL· GenBank· DDBJ
ANE16315.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290793
EMBL· GenBank· DDBJ
ANE16341.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290802
EMBL· GenBank· DDBJ
ANE16457.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290806
EMBL· GenBank· DDBJ
ANE16509.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290873
EMBL· GenBank· DDBJ
ANE17378.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290875
EMBL· GenBank· DDBJ
ANE17404.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290878
EMBL· GenBank· DDBJ
ANE17443.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290879
EMBL· GenBank· DDBJ
ANE17456.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290881
EMBL· GenBank· DDBJ
ANE17482.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290993
EMBL· GenBank· DDBJ
ANE18935.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290995
EMBL· GenBank· DDBJ
ANE18961.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290996
EMBL· GenBank· DDBJ
ANE18974.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290997
EMBL· GenBank· DDBJ
ANE18987.1
EMBL· GenBank· DDBJ
Genomic DNA
KU290999
EMBL· GenBank· DDBJ
ANE19013.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291002
EMBL· GenBank· DDBJ
ANE19052.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291004
EMBL· GenBank· DDBJ
ANE19078.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291005
EMBL· GenBank· DDBJ
ANE19091.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291007
EMBL· GenBank· DDBJ
ANE19117.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291009
EMBL· GenBank· DDBJ
ANE19143.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291083
EMBL· GenBank· DDBJ
ANE20104.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291085
EMBL· GenBank· DDBJ
ANE20130.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291091
EMBL· GenBank· DDBJ
ANE20208.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291093
EMBL· GenBank· DDBJ
ANE20234.1
EMBL· GenBank· DDBJ
Genomic DNA
KU291095
EMBL· GenBank· DDBJ
ANE20260.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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