A0A171KTP1 · A0A171KTP1_9BURK

  • Protein
    Pantothenate synthetase
  • Gene
    panC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.

Miscellaneous

The reaction proceeds by a bi uni uni bi ping pong mechanism.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site26-33ATP (UniProtKB | ChEBI)
Active site33Proton donor
Binding site57(R)-pantoate (UniProtKB | ChEBI)
Binding site57beta-alanine (UniProtKB | ChEBI)
Binding site144-147ATP (UniProtKB | ChEBI)
Binding site150(R)-pantoate (UniProtKB | ChEBI)
Binding site181-184ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionpantoate-beta-alanine ligase activity
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pantothenate synthetase
  • EC number
  • Short names
    PS
  • Alternative names
    • Pantoate--beta-alanine ligase
    • Pantoate-activating enzyme

Gene names

    • Name
      panC
    • ORF names
      AAV32_07675

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CG1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae > Kerstersia

Accessions

  • Primary accession
    A0A171KTP1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the pantothenate synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    275
  • Mass (Da)
    30,304
  • Last updated
    2016-07-06 v1
  • MD5 Checksum
    A7260CD01E20000DE378F9FDB1234975
MKIVHTPAELRTALADSQRPAFVPTMGNLHDGHLSLVRQAATFGDTTVASIFVNRLQFLPHEDFDSYPRTWEADCEKLRQNGCDILFAPREGDLYPAPQTFKVQPDPAIADILEGEFRPGFFTGVCTVVMKLFCCVQPAYAVFGKKDYQQLQVIRAMARQFALPVEIVAGATERAADGLALSSRNGYLGDAERQAAPQLHAALQALADAWHQGRRDLAAMESEARAQLASQGWKPDYLTLRQADTLQLPTPDESRLVALGAARLGNTRLIDNLEL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LBNE01000003
EMBL· GenBank· DDBJ
KKO72258.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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