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A0A167PSP5 · A0A167PSP5_9ENTR

  • Protein
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • Gene
    fabA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-2-decenoyl-ACP and then its isomerization to Z-3-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site71

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Molecular Functiontrans-2-decenoyl-acyl-carrier-protein isomerase activity
Biological Processunsaturated fatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • EC number
  • Alternative names
    • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
    • Beta-hydroxydecanoyl thioester dehydrase
    • Trans-2-decenoyl-[acyl-carrier-protein] isomerase
      (EC:5.3.3.14
      ) . EC:5.3.3.14 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      fabA
    • ORF names
      ABF77_22495
      , AYL25_06365
      , B9059_019315
      , HNS33_03285
      , J0A64_00965
      , OIPHN260_17410
      , SAMEA2273443_01134

Organism names

  • Taxonomic identifier
  • Strains
    • GN02692
    • e2161
    • E2161
    • PDA134
    • CRK0054
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter > Enterobacter cloacae complex

Accessions

  • Primary accession
    A0A167PSP5
  • Secondary accessions
    • A0A155YQ72
    • V3DZD2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    172
  • Mass (Da)
    18,955
  • Last updated
    2016-07-06 v1
  • MD5 Checksum
    5A58D8966767D52FFEDC383FED8F45AB
MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYSASDLKVGLFQDTSAF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP023447
EMBL· GenBank· DDBJ
BCL42239.1
EMBL· GenBank· DDBJ
Genomic DNA
LEDI01000110
EMBL· GenBank· DDBJ
KLP91252.1
EMBL· GenBank· DDBJ
Genomic DNA
JABJWE010000001
EMBL· GenBank· DDBJ
MBA2151862.1
EMBL· GenBank· DDBJ
Genomic DNA
JAFKCP010000001
EMBL· GenBank· DDBJ
MBU3765181.1
EMBL· GenBank· DDBJ
Genomic DNA
LSQV01000012
EMBL· GenBank· DDBJ
OBS90315.1
EMBL· GenBank· DDBJ
Genomic DNA
NEYZ02000077
EMBL· GenBank· DDBJ
RNT36919.1
EMBL· GenBank· DDBJ
Genomic DNA
FKDK01000003
EMBL· GenBank· DDBJ
SAA17173.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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