A0A166NSP8 · A0A166NSP8_STAPS
- ProteintRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
- GenemnmG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids624 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 11-16 | FAD (UniProtKB | ChEBI) | |||
Binding site | 123 | FAD (UniProtKB | ChEBI) | |||
Binding site | 178 | FAD (UniProtKB | ChEBI) | |||
Binding site | 270-284 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 367 | FAD (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | flavin adenine dinucleotide binding | |
Biological Process | tRNA methylation | |
Biological Process | tRNA wobble uridine modification |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nametRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus > Staphylococcus intermedius group
Accessions
- Primary accessionA0A166NSP8
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 542-613 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain | |||
Sequence similarities
Belongs to the MnmG family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length624
- Mass (Da)69,978
- Last updated2016-07-06 v1
- MD5 Checksum37A2FFA7AD51D475DEDB2D1986AD942A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAXKXX010000003 EMBL· GenBank· DDBJ | EGQ4384254.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
QEIT01000031 EMBL· GenBank· DDBJ | PWZ74986.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
QQPC01000026 EMBL· GenBank· DDBJ | REA82598.1 EMBL· GenBank· DDBJ | Genomic DNA |