A0A166MJ74 · A0A166MJ74_STAPS

Function

function

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

1722100200300400500600700
Type
IDPosition(s)Description
Binding site56ATP (UniProtKB | ChEBI)
Binding site381Mg2+ (UniProtKB | ChEBI)
Binding site411Mg2+ (UniProtKB | ChEBI)
Active site441Phosphohistidine intermediate
Binding site474ATP (UniProtKB | ChEBI)
Binding site570ATP (UniProtKB | ChEBI)
Binding site598ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentpolyphosphate kinase complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpolyphosphate kinase activity
Biological Processphosphorylation
Biological Processpolyphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyphosphate kinase
  • EC number
  • Alternative names
    • ATP-polyphosphate phosphotransferase
    • Polyphosphoric acid kinase

Gene names

    • Name
      ppk
    • ORF names
      DD902_07530
      , DV961_05090
      , EGV54_11200

Organism names

  • Taxonomic identifier
  • Strains
    • ST525 1
    • ST496-2
    • SPSE-18-VL-LA-PA-Ryan-0021
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus > Staphylococcus intermedius group

Accessions

  • Primary accession
    A0A166MJ74

Proteomes

Subcellular Location

PTM/Processing

Post-translational modification

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain18-123Polyphosphate kinase N-terminal
Domain134-309Polyphosphate kinase middle
Domain338-501Polyphosphate kinase C-terminal
Domain509-679Polyphosphate kinase C-terminal

Sequence similarities

Belongs to the polyphosphate kinase 1 (PPK1) family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    722
  • Mass (Da)
    83,921
  • Last updated
    2016-07-06 v1
  • Checksum
    67F80AF783CA5C1B
MKVTIEKGSLDLNHPDYYNNREVSWLDFNYRVLQEACDDQNPLLEQLKFIAIGSANLDEFFMVRVAGLKDQVKMGFNKPENKAQLTPQQQLKAIEQKNRQNVAFQYQRFNTLVETLKTYDVYLCKPDVLNEDMRKQLEQIFLNDILPTLTPLGIDAYRPFPKLNNKTLNIFVDIDTGDEINSAIVQIPTLLNRFITINEGNRQYIILIEDMISFFMGYLFKGYEILNTYTFRITRNADLTIHEDGAEDLLIEIERFLKERKSGAAVRLEIDHREQQEMQIDWLIDTLELEPQDVYYTNGPLDLTMVFELVDHLSHKLKDLKYERYTPQVPQSLGNDNVYDLALKRDIFFHHPYESFDPIVDFITEASEDPDTLAIKQTLYRVSSDSPIIEALKNAAENGKQVTVLVELKARFDEENNVHWAKMLEEAGCHVMYGMTHLKTHSKITLVVKRVNGKLVPFVHLGTGNYNDKTAKLYTDMGIITTNREIGEDAMNFFNYLSGYSMKPDYQQLIVAPYEIRDLFIERIDEEIESHRQHGNGKMMMKMNSLTDKALIKKLYEASQAGVQVKLIIRGICCLKPGIPGISDNIEVVSIVGRLLEHSRIYYFYNNGKEKIYLSSADMMTRNMIKRVEILFPILDKRIARRLVDFMHLQLSDNQKGRYQDASGVYHYVKNELAPINSQEYLMREAQEYGLALSKQNMIETGQPVRAKRNWMDRVKGHLKRK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAXKXX010000021
EMBL· GenBank· DDBJ
EGQ4385627.1
EMBL· GenBank· DDBJ
Genomic DNA
QEIT01000034
EMBL· GenBank· DDBJ
PWZ74647.1
EMBL· GenBank· DDBJ
Genomic DNA
QQPC01000028
EMBL· GenBank· DDBJ
REA82447.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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