A0A165BFW8 · A0A165BFW8_9PERO

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137750100150200250300350
TypeIDPosition(s)Description
Binding site80Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site94Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site179Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site193Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site198a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Etheostomatinae > Etheostoma

Accessions

  • Primary accession
    A0A165BFW8

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane26-53Helical
Transmembrane74-95Helical
Transmembrane110-130Helical
Transmembrane142-163Helical
Transmembrane175-197Helical
Transmembrane226-247Helical
Transmembrane285-305Helical
Transmembrane317-338Helical
Transmembrane344-369Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-206Cytochrome b/b6 N-terminal region profile
Domain207-377Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    377
  • Mass (Da)
    42,125
  • Last updated
    2016-07-06 v1
  • Checksum
    78A92452E624FDC3
LRKTHPLLKIANNSLVDLPAPSYISVWWNFGSLFGLCLITQILTGLFFAMHYTADIATAFSSVAHICRDVNYGWLIRNIHANGASFFFICIYLHIGRGLYYGSYLYKETWNIGVVLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGNTLVQWIWGGFSVDNATLTRFFAFHFLFPFVIAGATLIHLLFLHETGSNNPLGLNSDADKVSFHPYFSYKDLLGFAVLLIALTALALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLMVVPVLHTSKQRGITFRPLSQFLFWTLIADVAILTWIGGMPVEHPFIIIGQVASFLYFFLFLFLAPLAGWIENKALGWA

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue377

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KT880218
EMBL· GenBank· DDBJ
AMX23360.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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