A0A165BFW8 · A0A165BFW8_9PERO
- ProteinCytochrome b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids377 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 80 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 94 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 179 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 193 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 198 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | mitochondrial electron transport, ubiquinol to cytochrome c |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Encoded on
- Mitochondrion
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Etheostomatinae > Etheostoma
Accessions
- Primary accessionA0A165BFW8
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 26-53 | Helical | ||||
Sequence: VWWNFGSLFGLCLITQILTGLFFAMHYT | ||||||
Transmembrane | 74-95 | Helical | ||||
Sequence: WLIRNIHANGASFFFICIYLHI | ||||||
Transmembrane | 110-130 | Helical | ||||
Sequence: WNIGVVLLLLVMMTAFVGYVL | ||||||
Transmembrane | 142-163 | Helical | ||||
Sequence: VITNLLSAVPYVGNTLVQWIWG | ||||||
Transmembrane | 175-197 | Helical | ||||
Sequence: FFAFHFLFPFVIAGATLIHLLFL | ||||||
Transmembrane | 226-247 | Helical | ||||
Sequence: LLGFAVLLIALTALALFSPNLL | ||||||
Transmembrane | 285-305 | Helical | ||||
Sequence: LGGVLALLASILVLMVVPVLH | ||||||
Transmembrane | 317-338 | Helical | ||||
Sequence: LSQFLFWTLIADVAILTWIGGM | ||||||
Transmembrane | 344-369 | Helical | ||||
Sequence: FIIIGQVASFLYFFLFLFLAPLAGWI |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-206 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: LRKTHPLLKIANNSLVDLPAPSYISVWWNFGSLFGLCLITQILTGLFFAMHYTADIATAFSSVAHICRDVNYGWLIRNIHANGASFFFICIYLHIGRGLYYGSYLYKETWNIGVVLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGNTLVQWIWGGFSVDNATLTRFFAFHFLFPFVIAGATLIHLLFLHETGSNNPL | ||||||
Domain | 207-377 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GLNSDADKVSFHPYFSYKDLLGFAVLLIALTALALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLMVVPVLHTSKQRGITFRPLSQFLFWTLIADVAILTWIGGMPVEHPFIIIGQVASFLYFFLFLFLAPLAGWIENKALGWA |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length377
- Mass (Da)42,125
- Last updated2016-07-06 v1
- Checksum78A92452E624FDC3
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: L | ||||||
Non-terminal residue | 377 | |||||
Sequence: A |