A0A162PR45 · A0A162PR45_PHYB8

Function

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site352Nucleophile
Active site436
Active site438

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Uncharacterized protein

Gene names

    • ORF names
      PHYBLDRAFT_113947

Organism names

Accessions

  • Primary accession
    A0A162PR45

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-51Disordered
Compositional bias14-48Polar residues
Domain612-804ATP-grasp
Domain1151-1342ATP-grasp
Domain1408-1562MGS-like
Region1898-1919Disordered
Compositional bias1900-1919Basic and acidic residues

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,258
  • Mass (Da)
    248,338
  • Last updated
    2016-07-06 v1
  • Checksum
    E006372E002B7496
MASGFPIPSVADAGTAPSTGTNSRIPVPAANSTPLPFSLRSHSGPQPAATAIENPKDVTTAAFILQDGASFQGVSFGAEGKSISGECVFQTGMVGYPESLTDPSYRGQILVLTFPLIGNYGVPSREAMEEYLEGIPKYFESSEIHVAGLIVGNYSQDYSHYLAKSSLSDWLKENNVPALYGIDTRAMTKKIRKQGVLLGKILFRKADVSFIDSAASALGLSKGNDPGKWLNDFNDIEWVDPNKRNLVADVSIKEPKIYKPQASKAIKSSHGRTLRIIAVDVGMKYNQIRCFVYRGIELKVVPWDYDFSSEPTDTYDGLFISNGPGDPTMVKATINHLKTVLKNVRKPIFGICLGHQILALAANAKTVKMKYGNRGQNIPCTDKISGRCYITTQNHGYAVDSTTLPPDFQELFVNANDGSNEGIIHKTLPVFSVQFHPESAAGPRDTEFLFDVFIDSVKECADLGTLAPIAMPGGTKAENMIKNPRVSVNKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFLPVTPDFVRKVIEFEKPDGIYVTFGGQTALNVGIKLKDEFEDLGVKVLGTQIDTVITTEDRDLFAQALFEINEKCAPSASAISIDEALKAAEDIGYPVICRAAYALGGLGSGFANNENELIALCNKAFATSPQVLVEKSMKGWKEIEYEVVRDCQDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDDDYNMLRTTAVNVIRHLGVVGECNIQYALNPFSKEYCIIEVNARLSRSSALASKATGYPLAFVAAKLGLGIPLNEISNSVTKVTCACFEPSLDYIVVKIPRWDLKKFNRVSTALSSSMKSVGEVMAIGRTFEETIQKAIRAIDYNLVGFSAVSYLSKSDRNLDDDLRNPSDQRLFAIANAMNKGYTVDRIWELTNIDKWFLNKLMRIVNFDKRLEEFTKANIPGNLILSAKQLGFSDRQIANKINSNELSVRKLRQEYGVTPFVKQIDTVAAEFPAFTNYLYMTYNASDHDIAFKDNGVMVLGSGVYRIGSSVEFDWCAVRAIRTLRENHIKTVMVNYNPETVSTDYDEADRLYFENINMERVLDIYEIEHSSGVLMAMGGQTPNNIALPLFRQNVKVLGTSPEMIDNAENRYKFSRMCDQIGVDQPLWKELTSYDEADDFCNKVGYPVLVRPSYVLSGAAMNVVFSKDDLASYLNEAAAVSRDHPVVISKYIEEAKEIEMDAVALDGKMIMHVISEHVENAGVHSGDATLVLPPQDLDPETVRKIEIATAKIGRALNVTGPYNIQFIAKDNEIKVIECNVRASRSFPFVSKVLGVDLIEMATNAMLGLPVVPYPKVVIPKDYVGVKVPQFSFSRLSGADPVLGVEMASTGEVACFGRDKYSAYLKALLATGFTIPKKNILLSIGSYKEKMEMLPSVRKLHNLGYILFATAGTADFIQEHNIPVKYLEVLDGGSDVLKAEYSLQQHLAKNLIDLYINLPSRNRYRRPASYMSKGYRSRRMAVDYDIPLLTNVKCAKVFVEALARNPTGDYDILGIDYKTGHTSATLPGLFNINAYMGCSQSFGAISETSLSAGFTTLSVHASDIRDAASLEAANAIARKYAHTDYILNAISTVDNASRLGELSEDAAFVYINTDKIGSGEVSVFDSVFSSWPSSHLIVAEAKGTDLATILLLASFHNSVLHISNVTGKSDLDLIAMSKKKGLEVTCDIAVYSLFFTSEEFDNTKLLPTKKEQADLWKRLDIVDCFSIGSIPTKLCKELGKPVSPTDGIQETLPLLLDAVSKGRLSLKDISDRLHENPRKIFGLLPQPETYIEVELDRKHVCAKSDGSWSPLEGRTLSGLIHRVVVNETTVFMEGVCKSDGTLGRNMSTQALAVKSAVKKIVEKPMSSDTASDENIRRPNPEKHAKFGATPDGQLVLYEAPSFELSASLSRVLGRSPFYKKHILRAKQFDRNDLHLLFSVAQEMRALVERYGCVNLLQSRVITTMFFEPSTRTSSSFEAAMYRLGGKVVSVSAATSSVQKGESLADTVRTLGCYSDAIVLRHPQPGSAQIAAKYSKVPIINAGDGIGEHPTQAFLDIFTIREELGTVNGLSITLVGDLKNGRTVHSLVKLLTYYQVTINYVSPESLSMPADLIEEVKEAGVTQNTYRSLDEVIGSTDVLYMTRVQKERFSTEGEYNSVKDSFIINNDVLSKAQSHMIVLHPLPRVNEIEPEVDFDQRAAYFRQMRYGLYVRMALLALVMGTMRS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias14-48Polar residues
Compositional bias1900-1919Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV440984
EMBL· GenBank· DDBJ
OAD72146.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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