A0A162IVD4 · A0A162IVD4_METRR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site260Mg2+ 1 (UniProtKB | ChEBI)
Binding site260Mg2+ 2 (UniProtKB | ChEBI)
Binding site264Mg2+ 1 (UniProtKB | ChEBI)
Binding site296Mg2+ 2 (UniProtKB | ChEBI)
Binding site300Mg2+ 2 (UniProtKB | ChEBI)
Binding site322substrate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionisomerase activity
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase, mitochondrial
  • EC number
  • Alternative names
    • Acetohydroxy-acid reductoisomerase
    • Alpha-keto-beta-hydroxylacyl reductoisomerase

Gene names

    • ORF names
      NOR_05031

Organism names

Accessions

  • Primary accession
    A0A162IVD4

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain61-251KARI N-terminal Rossmann
Domain252-399KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    401
  • Mass (Da)
    44,691
  • Last updated
    2016-07-06 v1
  • Checksum
    10F2AE49D8426E48
MASRGFSKSLRAARQLATPRIQQRSYTAARQLVRAATAARPAVTVAQQQVRGVKTIDFAGHKEDVYERSDWPQEKLLDYFKNDTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWQDAIQDGWVPGKNLFEVDDAISRGTIVMNLLSDAAQSETWPAIKPQLVEGKTLYFSHGFSPVFKDLTKVDVPSNIDVILCAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAKERAIAMGVAIGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMFEACSTTARRGAIDWTPKFKDALKPVFNNLYDSVKDGSETQRSLDYNGQANYREKYEAEMEEIRNLEIWRAGKAVRALRPENQK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AZHC01000014
EMBL· GenBank· DDBJ
OAA42182.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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