A0A162HTG3 · A0A162HTG3_METRR
- ProteinAurora kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids396 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 136 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 155 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 204-206 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EFA | ||||||
Active site | 249 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 253-254 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EN | ||||||
Binding site | 267 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome passenger complex | |
Cellular Component | kinetochore | |
Cellular Component | spindle microtubule | |
Cellular Component | spindle midzone | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | regulation of cytokinesis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAurora kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium
Accessions
- Primary accessionA0A162HTG3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Cross-link | 251 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 70-100 | Polar residues | ||||
Sequence: LPSQAAQRKANNPGSPARKPLPSTGSARTSE | ||||||
Region | 70-116 | Disordered | ||||
Sequence: LPSQAAQRKANNPGSPARKPLPSTGSARTSEEGTEVVGKPSPIEQPS | ||||||
Domain | 126-379 | Protein kinase | ||||
Sequence: FEIGRPLGKGKFGRVYLARERTTGFICALKVLHKNEIQGGGVERQVRREIEIQSNLRHPNILQMFGHFHDSKRIFLILEFAGKGELYKHLRRENRFPEWKSAQYIAQMASALRYLHRKHVIHRDIKPENILMGIHGEIKISDFGWSVHAPNNRRKTMCGTLDYLPPEMIKPGSSDNYYNEKVDLWSLGVLTYEFLVGEAPFEDTPVMTQRRIQRADMSIPSFVSREASDLIKRLLVLDPEKRISLEQVQVHPWI |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length396
- Mass (Da)44,923
- Last updated2016-07-06 v1
- Checksum45595667B63BF80E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 70-100 | Polar residues | ||||
Sequence: LPSQAAQRKANNPGSPARKPLPSTGSARTSE |
Keywords
- Technical term