A0A158PRW2 · A0A158PRW2_BRUPA
- ProteinPurine nucleoside phosphorylase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Catalytic activity
- 2'-deoxyguanosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + guanine
Pathway
Purine metabolism; purine nucleoside salvage.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 47 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 78 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 98-100 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 131 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 214 | a purine D-ribonucleoside (UniProtKB | ChEBI) | |||
Binding site | 233 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 256 | a purine D-ribonucleoside (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | purine-nucleoside phosphorylase activity | |
Biological Process | nucleoside metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePurine nucleoside phosphorylase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia
Accessions
- Primary accessionA0A158PRW2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)32,625
- Last updated2016-06-08 v1
- MD5 Checksum11CD55037FF04A3CB08842933FEBAFE8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
UZAD01013225 EMBL· GenBank· DDBJ | VDN92538.1 EMBL· GenBank· DDBJ | Genomic DNA |