A0A158L138 · A0A158L138_9BURK

Function

function

This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

Catalytic activity

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionacetyl-CoA carboxylase activity
Molecular FunctionATP binding
Molecular Functionbiotin carboxylase activity
Molecular Functionmetal ion binding
Biological Processfatty acid biosynthetic process
Biological Processmalonyl-CoA biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biotin carboxylase
  • EC number
  • Alternative names
    • Acetyl-coenzyme A carboxylase biotin carboxylase subunit A

Gene names

    • ORF names
      AWB74_07816

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LMG 29317
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Caballeronia

Accessions

  • Primary accession
    A0A158L138

Proteomes

Interaction

Subunit

Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-445Biotin carboxylation
Domain120-317ATP-grasp

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    455
  • Mass (Da)
    50,301
  • Last updated
    2016-06-08 v1
  • Checksum
    788BCC1B52089A17
MFEKILIANRGEIALRIQRACRELGVKTVVVYSEADKEAKYVKLADEAVCIGPAPSNLSYLNMPALISAAEVTDAEAIHPGYGFLSENADFAERVEQSGFTFIGPRPETIRLMGDKVTAKQTMIKTGVPCVPGSEGALPDDPREIVKIARTIGYPVIIKAAGGGGGRGMRVVHTEAALVNAVNMTREEAGRAFGNPQVYMEKFLENPRHIEIQVLSDSFRNAIWLGERDCSMQRRHQKVIEEAPAPGIARRLIERIGDRCADACKKMGYLGAGTFEFLYENNEFYFIEMNTRVQVEHPVTELITGVDIVQEQIRIAAGEKLSIRQKDIQFKGHAIECRINAEDPFKFTPSPGRITSWHTAGGPGIRVDSHAYANYFVPPNYDSMIGKLIAYGATREQAINRMRIALSEMVVEGISTNIPLHREMMIDAKFVEGGTSIHYLENKLAARQAAVAEES

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FCOM02000077
EMBL· GenBank· DDBJ
SAL86709.1
EMBL· GenBank· DDBJ
Genomic DNA

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Disclaimer

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