A0A157ZB12 · A0A157ZB12_9BURK

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site238Mg2+ (UniProtKB | ChEBI)
Binding site268Mg2+ (UniProtKB | ChEBI)
Binding site270Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • ORF names
      AWB76_00454

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Caballeronia

Accessions

  • Primary accession
    A0A157ZB12

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain113-303Transketolase N-terminal
Domain493-706Pyruvate dehydrogenase E1 component middle
Domain721-855Transketolase-like C-terminal

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    897
  • Mass (Da)
    100,177
  • Last updated
    2016-06-08 v1
  • Checksum
    8BD071FEA6BA5D9A
MSAVPDEVLKYVANAKDDDPQETAEWLDALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVASQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSKEHGGDLVFVQGHSSPGVYSRAFLLGRLNEKQLNNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYMAARGMAKTEGRKVWAFLGDGETDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVSDWSDEDIWNLNRGGHDPHKIYAAFDAATKTKGAPTVILAKTIKGYGMGEHGQAMNITHQQKKLPIDTLKKFRDQFRLPLTDEQIADVPYLTFEEGSKELEYMRQKRMDLGGYLPSRREKAESLPVPALSAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQDGQKYIPEDSDQLMFYRESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMIPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASVPNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYITVMNENYEHPAIPQGDAVAADIIKGMYSFKKADAPAKAHVQLMGAGTIFNEVIAAAELLKNDWGVSADLWSVPSFTELAREGQAVERYNLLHPTEEKRVAHVTKLLTGAKGPVIASTDYIRALTDQIRAFVPQKFVVLGTDGYGRSDTREALRHFFEVDRYWVTLAALNALADEGTIERKVVAEAIRKYNLDPSKPNPMTV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FCOI02000001
EMBL· GenBank· DDBJ
SAK42735.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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