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A0A151BU14 · A0A151BU14_9MICO

Function

function

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site32a divalent metal cation (UniProtKB | ChEBI)
Binding site33a divalent metal cation (UniProtKB | ChEBI)
Binding site126a divalent metal cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentribonuclease H2 complex
Molecular Functionmanganese ion binding
Molecular FunctionRNA binding
Molecular FunctionRNA-DNA hybrid ribonuclease activity
Biological ProcessDNA replication, removal of RNA primer
Biological Processmismatch repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease HII
  • EC number
  • Short names
    RNase HII

Gene names

    • Name
      rnhB
    • ORF names
      AZH51_12960

Organism names

  • Taxonomic identifier
  • Strain
    • NY16-3462-2
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Dermacoccaceae > Branchiibius

Accessions

  • Primary accession
    A0A151BU14

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain26-232RNase H type-2

Sequence similarities

Belongs to the RNase HII family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    236
  • Mass (Da)
    25,593
  • Last updated
    2016-06-08 v1
  • MD5 Checksum
    BB79FBA6D663BB3221E3CEC687452C8F
MRTRRTGTSKVPTLRTERALQREGYRLLAGMDEVGRGALAGPVSVGVVVIDETCRTAPQGVRDSKLLTPAAREAMVPRVRRWALAYAVGHASAAEIDQIGIIAALRLAGTRALAALPVRPDLVILDGNHDWLTDPARVGLFAELAQPTLPPVRTLIKADMKCSSVAAASVLAKVERDGMLTELHEQYPHYQWAANKGYSAPEHLTALDEHGPCELHRRSWRRFVAGDAAVDLEGVS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LVCF01000043
EMBL· GenBank· DDBJ
KYH43346.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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