A0A151BT63 · A0A151BT63_9MICO

  • Protein
    Succinate--CoA ligase [ADP-forming] subunit beta
  • Gene
    sucC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site49ATP (UniProtKB | ChEBI)
Binding site56-58ATP (UniProtKB | ChEBI)
Binding site98ATP (UniProtKB | ChEBI)
Binding site103ATP (UniProtKB | ChEBI)
Binding site195Mg2+ (UniProtKB | ChEBI)
Binding site209Mg2+ (UniProtKB | ChEBI)
Binding site260substrate; ligand shared with subunit alpha
Binding site327-329substrate; ligand shared with subunit alpha

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentsuccinate-CoA ligase complex
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Molecular Functionsuccinate-CoA ligase (ADP-forming) activity
Molecular Functionsuccinate-CoA ligase (GDP-forming) activity
Biological Processsuccinyl-CoA metabolic process
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate--CoA ligase [ADP-forming] subunit beta
  • EC number
  • Alternative names
    • Succinyl-CoA synthetase subunit beta
      (SCS-beta
      )

Gene names

    • Name
      sucC
    • ORF names
      AZH51_06505

Organism names

  • Taxonomic identifier
  • Strain
    • NY16-3462-2
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Dermacoccaceae > Branchiibius

Accessions

  • Primary accession
    A0A151BT63

Proteomes

Subcellular Location

Interaction

Subunit

Heterotetramer of two alpha and two beta subunits.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-245ATP-grasp

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    40,987
  • Last updated
    2016-06-08 v1
  • Checksum
    487F14C6600330EC
MDLFEYQARDMFEAHGVPVLAGKTATTPQEARAAAEEIGALSGGVSVVKAQVKTGGRGKAGGVKVAKSADEAEQYAEQILGMDIKGHTVGTVMIAQGAQIAEEYYFSVLLDRANRSYLAMCSKEGGMEIEQLAVERPEALARIPVDPNVGIDQAKADEIVAAAGFDADTAAKVAPVLIKLWDVYAGEDATLVEVNPLVKTAQGDIVALDGKVTLDANADFRHPDHAALEDVAAADPLEAAAKEKGLNYVKLDGDVGIIGNGAGLVMSTLDVVAYAGEEFTNPAGEHPKPANFLDIGGGASAEVMTNGLNIILGDEQVKSVFVNVFGGITACDEVAKGIVGALDALGDSATKPLVVRLDGNAVDEGRAILAERNHPLVTIEATMDGAAAKAAELAAAK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LVCF01000046
EMBL· GenBank· DDBJ
KYH43095.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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