A0A151BT09 · A0A151BT09_9MICO
- ProteinPolyphosphate kinase
- Geneppk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids743 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Catalytic activity
- [phosphate](n) + ATP = [phosphate](n+1) + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 88 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 424 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 454 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 484 | Phosphohistidine intermediate | ||||
Sequence: H | ||||||
Binding site | 517 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 613 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 641 | ATP (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | polyphosphate kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | polyphosphate kinase activity | |
Biological Process | phosphorylation | |
Biological Process | polyphosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyphosphate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Dermacoccaceae > Branchiibius
Accessions
- Primary accessionA0A151BT09
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Post-translational modification
An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 50-155 | Polyphosphate kinase N-terminal | ||||
Sequence: FLDREISWLQFNERVLQLAQDPGVPLLERARFLAIFASNLDEFFMVRVAGLKRRIATGLAVRSASGLEPREVLDEISRAAHQLMDAHAGVFQVHIRPALADEGVRI | ||||||
Domain | 165-345 | Polyphosphate kinase middle | ||||
Sequence: DREHLSTLFRQQIYPVLTPLAVDPAHPFPYISGLSLNLAVILINPKTEREHFARVKVPPLLPRLLRLPTAEGDDDLYDARFVTLEDVIAEHLQHLFPGMEVREHFTFRVTRNEDLEVEEDDAENLLTALEKELTRRRFGPPVRLEVADDIDDHVLDLLVRELGVHDGEVYRLPEPLDLTGL | ||||||
Domain | 380-543 | Polyphosphate kinase C-terminal | ||||
Sequence: VLAAMRRGDVLLHHPYDSFSTSVQAFLEQAAADPQVLAIKQTLYRTSGDSPIIDALIDAADAGKQVLAVVEIKARFDEENNISWARKLERAGVHVVYGIVGLKTHAKLSMVVRQEGDTLRRYCHVGTGNYNPKTARLYEDLGLLTCDPEVGEDLSRLFNQLSGM | ||||||
Domain | 552-714 | Polyphosphate kinase C-terminal | ||||
Sequence: LLVAPRSMRNGLVEQIDRVIAAKREGKDARIQFKINSLVDEQIIDALYRASQAGVPVDIFVRGICAIRPGVDGLSETIRVRSVLGRFLEHSRIFRFAVEGEGDVTYIGSADMMHRNLDRRVEALVRISSPRHLSELAGLIDNGMSDATSSWHLGGDGLWERHN |
Sequence similarities
Belongs to the polyphosphate kinase 1 (PPK1) family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length743
- Mass (Da)83,421
- Last updated2016-06-08 v1
- ChecksumA01D77CD7E029D40
Keywords
- Technical term