A0A141R7K3 · A0A141R7K3_SVCV
- ProteinRNA-directed RNA polymerase L
- GeneL
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2095 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- GTP + H2O = GDP + H+ + phosphate
- a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
- a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H+ + S-adenosyl-L-homocysteine
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | host cell cytoplasm | |
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity | |
Molecular Function | RNA-dependent RNA polymerase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRNA-directed RNA polymerase L
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Alpharhabdovirinae > Sprivivirus
- Virus hosts
Accessions
- Primary accessionA0A141R7K3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 825-843 | Helical | ||||
Sequence: YHYFANFCLMMIAMHNPAI | ||||||
Transmembrane | 864-886 | Helical | ||||
Sequence: AVTLYLDPSLGGVCGISLARFLI |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 587-773 | RdRp catalytic | ||||
Sequence: ICIANHIDYEKWNNHQRKESNGPVFRVMGQFLGYPRLFERTHEFFESSLIYYNGRPDLMDVRGDSLVNTTDRIVCWEGQAGGLEGLRQKGWSVLNLLVINRESSIRNTVVKVLAQGDNQVICTQYKTKNYKNEEELIMLLTAMVENNQTIMNGIIAGTGKLGLIINNDETMQSADYLNYGKVPVFRG | ||||||
Domain | 1625-1822 | Mononegavirus-type SAM-dependent 2'-O-MTase | ||||
Sequence: RISQQATGAHYKLRSLLKGMKIHYQDAIGCGDGSGGLSSCLLRENKHCRVIFNSLLELTGNTLRGSTPDPPSAINGIPQVRDRCVNLTSVWEHPSDLSHPDTWKYFGELKAQCNMDIDLIVMDMEVQDIDISRRIEQNLRDHVHSLLSRHGTVIYKTYMTILSENERSVLDIVGVLFEDVQLCQTQYSSSQTSEVYCV |
Sequence similarities
Belongs to the rhabdoviridae protein L family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,095
- Mass (Da)238,286
- Last updated2016-06-08 v1
- Checksum570A01BAC692A5C9