A0A140LJ70 · A0A140LJ70_MOUSE
- Proteintype I protein arginine methyltransferase
- GenePrmt1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids254 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H+This reaction proceeds in the forward direction.
- L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H+This reaction proceeds in the forward direction.
- N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleoplasm | |
Molecular Function | protein-arginine N-methyltransferase activity | |
Biological Process | peptidyl-arginine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametype I protein arginine methyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A140LJ70
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 74-144 | Methyltransferase | ||||
Sequence: VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIYTVK | ||||||
Domain | 95-241 | Protein arginine N-methyltransferase | ||||
Sequence: KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQ |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length254
- Mass (Da)28,909
- Last updated2016-05-11 v1
- ChecksumC31E6D59301B42B2
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9JIF0 | ANM1_MOUSE | Prmt1 | 371 | ||
A0A171KXD3 | A0A171KXD3_MOUSE | Prmt1 | 318 | ||
A0A140LJF4 | A0A140LJF4_MOUSE | Prmt1 | 193 | ||
A0A140LJG1 | A0A140LJG1_MOUSE | Prmt1 | 55 | ||
A0A140LJ68 | A0A140LJ68_MOUSE | Prmt1 | 122 | ||
A0A140LIF7 | A0A140LIF7_MOUSE | Prmt1 | 113 | ||
A0A140LI33 | A0A140LI33_MOUSE | Prmt1 | 164 | ||
A0A140LHS4 | A0A140LHS4_MOUSE | Prmt1 | 217 | ||
A0A140LHF7 | A0A140LHF7_MOUSE | Prmt1 | 208 |
Keywords
- Technical term