Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos.Zhang D., Deng W., Jiang T., Zhao Y., Bai D., Tian Y., Kong S., Zhang L., Wang H.[...], Lu Z.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCJ Cell Physiol 239:e31244-e31244 (2024)Mapped to99+
gamma-Linolenic acid in maternal milk drives cardiac metabolic maturation.Paredes A., Justo-Mendez R., Jimenez-Blasco D., Nunez V., Calero I., Villalba-Orero M., Alegre-Marti A., Fischer T., Gradillas A.[...], Ricote M.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCNature 618:365-373 (2023)Mapped to99+
ZFP750 affects the cutaneous barrier through regulating lipid metabolism.Butera A., Agostini M., Cassandri M., De Nicola F., Fanciulli M., D'Ambrosio L., Falasca L., Nardacci R., Wang L.[...], Melino G.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCSci Adv 9:eadg5423-eadg5423 (2023)Mapped to99+
Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of omega-O-acylceramide in mice.Kato A., Ito M., Sanaki T., Okuda T., Tsuchiya N., Yoshimoto R., Yukioka H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCBiochim Biophys Acta Mol Cell Biol Lipids 1867:159085-159085 (2022)Mapped to27
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Chitraju C., Fischer A.W., Farese R.V. Jr., Walther T.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCCell Rep 33:108348-108348 (2020)Mapped to6
CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4alpha and DGAT2 expression.Tan S.Y., Little H.C., Sarver D.C., Watkins P.A., Wong G.W.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCFEBS Lett 594:3227-3239 (2020)Mapped to15
The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.Thayer T.E., Lino Cardenas C.L., Martyn T., Nicholson C.J., Traeger L., Wunderer F., Slocum C., Sigurslid H., Shakartzi H.R.[...], Malhotra R.View abstractCategoriesFunction, ExpressionSourceMGI: 1915050PubMedEurope PMCSci Rep 10:9831-9831 (2020)Mapped to12
Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.Mayeuf-Louchart A., Lancel S., Sebti Y., Pourcet B., Loyens A., Delhaye S., Duhem C., Beauchamp J., Ferri L.[...], Duez H.View abstractCategoriesFunction, ExpressionSourceMGI: 1915050PubMedEurope PMCCell Rep 29:1410-1418.e6 (2019)Mapped to99+
Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice.Gluchowski N.L., Gabriel K.R., Chitraju C., Bronson R.T., Mejhert N., Boland S., Wang K., Lai Z.W., Farese R.V. Jr., Walther T.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCHepatology 70:1972-1985 (2019)Mapped to4
The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes.Chitraju C., Walther T.C., Farese R.V. Jr.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCJ Lipid Res 60:1112-1120 (2019)Mapped to4
ER stress mediated degradation of diacylglycerol acyltransferase impairs mitochondrial functions in TMCO1 deficient cells.Wang X., Wang Q.C., Sun Z., Li T., Yang K., An C., Guo C., Tang T.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCBiochem Biophys Res Commun 512:914-920 (2019)Mapped to8
Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2.Irshad Z., Chmel N., Adya R., Zammit V.A.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 1915050PubMedEurope PMCJ Lipid Res 60:111-120 (2019)Mapped to6
The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function.Roe N.D., Handzlik M.K., Li T., Tian R.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCSci Rep 8:4983-4983 (2018)Mapped to8
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O- acylceramide synthesis and skin permeability barrier.Pichery M., Huchenq A., Sandhoff R., Severino-Freire M., Zaafouri S., Opalka L., Levade T., Soldan V., Bertrand-Michel J.[...], Jonca N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCHum Mol Genet 26:1787-1800 (2017)Mapped to65
Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat.Hung Y.H., Carreiro A.L., Buhman K.K.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 1915050PubMedEurope PMCBiochim Biophys Acta Mol Cell Biol Lipids 1862:600-614 (2017)Mapped to6
Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.Kaltenecker D., Mueller K.M., Benedikt P., Feiler U., Themanns M., Schlederer M., Kenner L., Schweiger M., Haemmerle G., Moriggl R.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCDiabetologia 60:296-305 (2017)Mapped to35
Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.Bose S.K., Hutson I., Harris C.A.View abstractCategoriesFunction, ExpressionSourceMGI: 1915050PubMedEurope PMCEndocrinology 157:4943-4960 (2016)Mapped to99+
An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.Segerer G., Hadamek K., Zundler M., Fekete A., Seifried A., Mueller M.J., Koentgen F., Gessler M., Jeanclos E., Gohla A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915050PubMedEurope PMCSci Rep 6:35160-35160 (2016)Mapped to57
Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome.Brandt C., McFie P.J., Stone S.J.View abstractCategoryFunctionSourceMGI: 1915050PubMedEurope PMCBiochem J 473:3621-3637 (2016)Mapped to7
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.Fonseca T.L., Fernandes G.W., McAninch E.A., Bocco B.M., Abdalla S.M., Ribeiro M.O., Mohacsik P., Fekete C., Li D.[...], Bianco A.C.View abstractCategoryExpressionSourceMGI: 1915050PubMedEurope PMCProc Natl Acad Sci U S A 112:14018-14023 (2015)Mapped to99+
Tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice.Kim Y.K., Zuccaro M.V., Costabile B.K., Rodas R., Quadro L.View abstractCategoryExpressionSourceMGI: 1915050PubMedEurope PMCArch Biochem Biophys 572:11-18 (2015)Mapped to32
Characterization of the interaction of diacylglycerol acyltransferase-2 with the endoplasmic reticulum and lipid droplets.McFie P.J., Jin Y., Banman S.L., Beauchamp E., Berthiaume L.G., Stone S.J.View abstractCategorySubcellular LocationSourceMGI: 1915050PubMedEurope PMCBiochim Biophys Acta 1841:1318-1328 (2014)Mapped to4