Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.Perelman B., Dafni N., Naiman T., Eli D., Yaakov M., Feng T.L.Y., Sinha S., Weber G., Khodaei S.[...], Canaani D.View abstractCategoriesSequencesSourceMGI: 1925860PubMedEurope PMCGenomics 41:397-405 (1997)Cited in1Mapped to5
Distinct roles of UVRAG and EGFR signaling in skeletal muscle homeostasis.Kim M.J., Febbraro D., Farkona S., Gillmore T., Son J.E., Regeenes R., Chang H.H., Pollock-Tahiri E., Yang J.[...], Woo M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1925860PubMedEurope PMCMol Metab 47:101185-101185 (2021)Mapped to15
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.Quach C., Song Y., Guo H., Li S., Maazi H., Fung M., Sands N., O'Connell D., Restrepo-Vassalli S.[...], Liang C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1925860PubMedEurope PMCNat Commun 10:5681-5681 (2019)Mapped to6
UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity.An L., Hu X.W., Zhang S., Hu X., Song Z., Naz A., Zi Z., Wu J., Li C.[...], Zhu H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1925860PubMedEurope PMCSci Rep 7:43251-43251 (2017)Mapped to6
Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.Cheng Z., Zhu Q., Dee R., Opheim Z., Mack C.P., Cyr D.M., Taylor J.M.View abstractCategoriesFunctionSourceMGI: 1925860PubMedEurope PMCJ Biol Chem 292:2065-2079 (2017)Mapped to38
Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency.Kim Y., Kang Y.S., Lee N.Y., Kim K.Y., Hwang Y.J., Kim H.W., Rhyu I.J., Her S., Jung M.K.[...], Ryu H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1925860PubMedEurope PMCAutophagy 11:796-811 (2015)Mapped to15
Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.Afzal S., Hao Z., Itsumi M., Abouelkheer Y., Brenner D., Gao Y., Wakeham A., Hong C., Li W.Y.[...], Mak T.W.View abstractCategoriesFunctionSourceMGI: 1925860PubMedEurope PMCProc Natl Acad Sci U S A 112:1119-1124 (2015)Mapped to6
mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.Kim Y.M., Jung C.H., Seo M., Kim E.K., Park J.M., Bae S.S., Kim D.H.View abstractCategoriesInteractionSourceMGI: 1925860PubMedEurope PMCMol. Cell 57:207-218 (2015)Cited in1Mapped to30
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.McKnight N.C., Zhong Y., Wold M.S., Gong S., Phillips G.R., Dou Z., Zhao Y., Heintz N., Zong W.X., Yue Z.View abstractCategoriesFunction, InteractionSourceMGI: 1925860PubMedEurope PMCPLoS Genet. 10:E1004626-E1004626 (2014)Cited in2Mapped to23
Essential role for UVRAG in autophagy and maintenance of cardiac function.Song Z., An L., Ye Y., Wu J., Zou Y., He L., Zhu H.View abstractCategoriesFunctionSourceMGI: 1925860PubMedEurope PMCCardiovasc Res 101:48-56 (2014)Mapped to6
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.Zhao Z., Oh S., Li D., Ni D., Pirooz S.D., Lee J.H., Yang S., Lee J.Y., Ghozalli I.[...], Liang C.View abstractCategoriesFunction, InteractionSourceMGI: 1925860PubMedEurope PMCDev. Cell 22:1001-1016 (2012)Cited in1Mapped to19
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.Takahashi Y., Coppola D., Matsushita N., Cualing H.D., Sun M., Sato Y., Liang C., Jung J.U., Cheng J.Q.[...], Wang H.G.View abstractCategoriesInteractionSourceMGI: 1925860PubMedEurope PMCNat. Cell Biol. 9:1142-1151 (2007)Cited in2Mapped to18