A0A140H909 · A0A140H909_SINWO
- ProteinCatalase
- GeneCAT
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids512 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the degradation of hydrogen peroxide (H2O2) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.
Catalytic activity
- 2 H2O2 = O2 + 2 H2O
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 72 | ||||
Active site | 145 | ||||
Binding site | 355 | Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | peroxisome | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to hydrogen peroxide |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCatalase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Heteroconchia > Palaeoheterodonta > Unionida > Unionoidea > Unionidae > Unioninae > Sinanodonta
Accessions
- Primary accessionA0A140H909
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-35 | Polar residues | |||
Region | 1-38 | Disordered | |||
Domain | 25-410 | Catalase core | |||
Compositional bias | 396-410 | Polar residues | |||
Region | 396-417 | Disordered | |||
Sequence similarities
Belongs to the catalase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length512
- Mass (Da)58,064
- Last updated2016-05-11 v1
- MD5 Checksum1DDCDB6A0896707B1A46272090749529
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-35 | Polar residues | |||
Compositional bias | 396-410 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KU363383 EMBL· GenBank· DDBJ | AMO00631.1 EMBL· GenBank· DDBJ | mRNA |