A0A140D6E3 · A0A140D6E3_9ENTR

  • Protein
    4-hydroxybenzoate octaprenyltransferase
  • Gene
    hdbP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4-hydroxybenzoate decaprenyltransferase activity
Molecular Function4-hydroxybenzoate nonaprenyltransferase activity
Molecular Function4-hydroxybenzoate octaprenyltransferase activity
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxybenzoate octaprenyltransferase
  • EC number
  • Alternative names
    • 4-HB polyprenyltransferase

Gene names

    • Name
      hdbP
    • Synonyms
      ubiA

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NT18-21Contig1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0A140D6E3

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-40Helical
Transmembrane46-70Helical
Transmembrane99-132Helical
Transmembrane152-182Helical
Transmembrane213-233Helical
Transmembrane239-257Helical
Transmembrane269-288Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the UbiA prenyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    290
  • Mass (Da)
    32,602
  • Last updated
    2016-05-11 v1
  • Checksum
    7BCEEDE3DB05DCED
MERSLRPNKLLAYHQLMRTDKPIGALLLLWPTLWALWVAAPGVPPLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVSEKEARILFAVLVLLSFLLVLTLNTMTILLSVAGLALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMLLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQACVLVLMAVIGWLNGLHWEFYWSILIAGALFVYQQKLIRNRERGPCFQAFLNNNYVGLVLFIGLAMSYWQF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU505137
EMBL· GenBank· DDBJ
AMK07429.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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