A0A140CUL8 · A0A140CUL8_ONCMY

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentacetylcholine-gated channel complex
Cellular Componentneuron projection
Cellular Componentpostsynaptic membrane
Molecular Functionacetylcholine binding
Molecular Functionacetylcholine receptor activity
Molecular Functionacetylcholine-gated monoatomic cation-selective channel activity

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Nicotinic acetylcholine receptor subunit alpha 7

Gene names

    • Name
      CHRNA7

Organism names

Accessions

  • Primary accession
    A0A140CUL8

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein
Postsynaptic cell membrane
; Multi-pass membrane protein
Synaptic cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane245-270Helical
Transmembrane276-294Helical
Transmembrane306-329Helical
Transmembrane555-575Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain41-244Neurotransmitter-gated ion-channel ligand-binding
Domain251-384Neurotransmitter-gated ion-channel transmembrane
Region363-401Disordered
Compositional bias378-393Polar residues
Domain512-571Neurotransmitter-gated ion-channel transmembrane

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    587
  • Mass (Da)
    65,414
  • Last updated
    2016-05-11 v1
  • Checksum
    C10CC0B93B663B50
MQLFDTFYFCHLSSEIPCSPFPSISLSSVLLSVSVQGPHQRTLLKNLLKDYNRMERPVGNDSHSLTVFFSISLMQIMDVDEKNQVVTTNIWLRMSWFDHYLQWNQSEYPGVKNLRFTTDQVWTPDILLYNSADDDFDSTFKTNVLVNSSGFAEYLPPGIFMSTCNVDVRWFPFDIQKCEMKFGSWTYDGWLMDLQMNEADISGYMSNGEWDLVGVPGTRSEVFYDCCKEPYPDVTFVVTIRRRTLYYALNLLIPCVLLSSMTLLIFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSIPLIGQYFASTMIIVGMSVIATTVVLQYHHHDPNGGQMPKWVNVVLLQWVAWFLRMKRPGESDDPERPPCAPHLRRCSSSSQSGSIANPPDPTLHQLHPQNLVPLQAGPQHLGHPHLHAQSSANNNGNLLYIGFQNLDDPPLLPDHIQNYSISAGPPRVAGSPPPHLPPPFCSPPPPPTPNADTVGCPSTISSGGVFGMGGGGQYSAGRIGDPQLQAILEEVRYMADRFREQDETESVADQWKFAAAVIDRLCLVAFSVFNIICTIAILMSAPNFVEAASKDFF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias378-393Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KT634308
EMBL· GenBank· DDBJ
AMH93715.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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