A0A133N8A3 · A0A133N8A3_9FUSO

  • Protein
    7-cyano-7-deazaguanine synthase
  • Gene
    queC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site7-17ATP (UniProtKB | ChEBI)
Binding site194Zn2+ (UniProtKB | ChEBI)
Binding site202Zn2+ (UniProtKB | ChEBI)
Binding site205Zn2+ (UniProtKB | ChEBI)
Binding site208Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionligase activity, forming carbon-nitrogen bonds
Molecular Functionzinc ion binding
Biological Processqueuosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    7-cyano-7-deazaguanine synthase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine synthase
    • PreQ(0) synthase
    • Queuosine biosynthesis protein QueC

Gene names

    • Name
      queC
    • ORF names
      HMPREF3206_01723

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CMW8396
  • Taxonomic lineage
    Bacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium

Accessions

  • Primary accession
    A0A133N8A3

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the QueC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    25,225
  • Last updated
    2016-06-08 v1
  • Checksum
    229A018302516751
MKVLVLLSGGLDSTTCLAIAVDKYGADQVVALSASYGQKHTKEILSARAIAKYYQVELLELNLSKIFSYSNCSLLSHSTEEVPHHSYAEQLNQQEEEILSTYVPFRNGLFLSTAASIALSKECSIILYGAHSDDAAGNAYPDCSPAFNEAMNTAIYEGSGRQVKVEAPFIGLHKKDIVKLGLTLQVPYELTWSCYEGKEHSCGECGTCIDREKAFEENGTIDPLVKIRGGK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LRPX01000098
EMBL· GenBank· DDBJ
KXA12535.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp