A0A133KHC9 · A0A133KHC9_9FIRM

  • Protein
    RNA polymerase sigma factor SigA
  • Gene
    sigA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for dna binding.

160650100150200250300350400450500550600
TypeIDPosition(s)Description
DNA binding568-587H-T-H motif

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionDNA binding
Molecular Functionsigma factor activity
Biological ProcessDNA-templated transcription initiation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase sigma factor SigA

Gene names

    • Name
      sigA
    • ORF names
      HMPREF3200_00455

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MJR8151
  • Taxonomic lineage
    Bacteria > Bacillota > Tissierellia > Tissierellales > Peptoniphilaceae > Anaerococcus

Accessions

  • Primary accession
    A0A133KHC9

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Interacts transiently with the RNA polymerase catalytic core.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, motif, domain.

TypeIDPosition(s)Description
Region72-91Disordered
Region374-444Sigma-70 factor domain-2
Motif398-401Interaction with polymerase core subunit RpoC
Domain398-411RNA polymerase sigma-70
Region453-529Sigma-70 factor domain-3
Region542-595Sigma-70 factor domain-4
Domain567-593RNA polymerase sigma-70

Sequence similarities

Belongs to the sigma-70 factor family. RpoD/SigA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    606
  • Mass (Da)
    69,370
  • Last updated
    2016-06-08 v1
  • Checksum
    91312F3457672B18
MTSDDNKLLDDDVLKEIIEEFQSISESQDGLITYSQIYTFENFKEMEDESKKFVINQIINLGIEIVENSETVLEEEEENTEDLDDEIADDKEDLDDDINEKELEEDISKSVDIMAGVKVDDPVKMYLKEIGKVSLLTATEEIILARRMEMGEIAKKKLENVKFNKQNKTKLANDIFFGDLAKILMLANQSLRDKGSVDEKSKREISGLISMGKLFKQIMDNDLDKETLEELKTKVMICNIAENAVNEDDLNESQANSLCDLFDSFDHMLNITKSDEIVNLVYISFNDILSKAANKEQIKTNDRMILDDFINTSSRAEKIYDGVGLSKKELSEIDESIELRDLAFKIINEDILNDDDFMELKRAVINSKRAKQKLAETNLRLVVSIAKKYVGRGMSFLDLIQEGNMGLMKAVDKYDYNRGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLVRIQRQLVQDLGRDPSNEEIAEQMGIEVDKVQEIRKISQEPVSLETPIGEEDDSHLGDFIEDDTAVDPGEAANYTMLREQLNDVLSCLGAREKRVLQLRFGLIDGTPRTLEEVGKEFDVTRERIRQIEAKALRKLKSPNKSELLKDFL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LRPM01000010
EMBL· GenBank· DDBJ
KWZ78972.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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