Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A127EGN2 · A0A127EGN2_CLOPF

Function

function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.

Features

Showing features for active site, binding site.

138650100150200250300350
Type
IDPosition(s)Description
Active site38Proton acceptor; specific for D-alanine
Binding site136substrate
Active site267Proton acceptor; specific for L-alanine
Binding site315substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionalanine racemase activity
Molecular Functionpyridoxal phosphate binding
Biological ProcessD-alanine biosynthetic process
Biological Processpeptidoglycan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alanine racemase
  • EC number

Gene names

    • ORF names
      JFP838_04765

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JP838
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Clostridium

Accessions

  • Primary accession
    A0A127EGN2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue38N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain246-374Alanine racemase C-terminal

Sequence similarities

Belongs to the alanine racemase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    386
  • Mass (Da)
    42,960
  • Last updated
    2016-06-08 v1
  • MD5 Checksum
    1FFB02568CACFEBCEA6101B9BD2EB473
MDICVRPVWAEIDLDIIANNMKEIRNLVGEKEIIAVVKANAYGHGALDIASTLLENGASRLAVAIITEADELRDAGITAPIMILGYTPINFAENLINNEIEQTVYDVEYAKELSDFALKLGKKAKIHIAIDTGMGRIGFLPNEEGLNKVLEICSLPGVEVIGLFTHFSTSDEKDKTYTYEQFSKLTAFNKALEDNGIHIPLKHASNSGAIMDLPETYLDGVRCGIISYGYYPSEEVKKENLKLKPALTLKTNVAFVKELDEDMYVSYGRTYKTEKKSKIATLPIGYADGYSRLLSGKAKVIIKGQFANVIGRVCMDQCMIDVTHIEDVKIGDEVILLGEENGLKFDANDMAEIMGTINYEILCMISHRVPRIYKKNNEIVKVRNYI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP010994
EMBL· GenBank· DDBJ
AMN35092.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help