A0A125YG55 · A0A125YG55_CYAM1

Function

function

Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Cellular Componentcytosol
Molecular Functionporphobilinogen synthase activity
Molecular Functionzinc ion binding
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-aminolevulinic acid dehydratase
  • EC number

Gene names

    • ORF names
      CYME_CMD104C

Organism names

Accessions

  • Primary accession
    A0A125YG55

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region37-76Disordered
Compositional bias41-55Polar residues

Sequence similarities

Belongs to the ALAD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    402
  • Mass (Da)
    44,106
  • Last updated
    2016-04-13 v1
  • Checksum
    52B631F98E49E4F7
MFVAKVPLSIRGQPSLNAIKPSATAPKRRKLSLFAVAAPRRSSEQASTSANSPLLPRNDKGEPWVVQRSRPRRNRKTNAVREMVRENVVSPGNLVYPVFIHDEDHDEDIDVMPGCKRLSIQSLLKHAAQALDLGIGHIILFPKIEEHLKSNTADECYNPKGLVPSAIKALKEKFGSRITVWTDIALDPYSDQGHDGIVSNDSLGDGGCARILNDETVEQLCRQALCHARAGADIVAPSDMMDGRVGAIRDALDEEGFTDVSIVSYAAKYASSFYGPFRGALDSAPRETSRAPRDKKTYQMDPGNAREALREAAADLEEGADMLLVKPGVPYLDIIHLLYDAFPVPIAAYHVSGEYAMIKAAAQRGWIDEKQVVLETLLSLKRAGATSILTYYALEAAKWMQE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias41-55Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP006486
EMBL· GenBank· DDBJ
BAM79178.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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