A0A125YG55 · A0A125YG55_CYAM1
- ProteinDelta-aminolevulinic acid dehydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids402 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
Catalytic activity
- 2 5-aminolevulinate = porphobilinogen + 2 H2O + H+
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | cytosol | |
Molecular Function | porphobilinogen synthase activity | |
Molecular Function | zinc ion binding | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDelta-aminolevulinic acid dehydratase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Rhodophyta > Bangiophyceae > Cyanidiales > Cyanidiaceae > Cyanidioschyzon
Accessions
- Primary accessionA0A125YG55
Proteomes
Genome annotation databases
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 37-76 | Disordered | ||||
Sequence: AAPRRSSEQASTSANSPLLPRNDKGEPWVVQRSRPRRNRK | ||||||
Compositional bias | 41-55 | Polar residues | ||||
Sequence: RSSEQASTSANSPLL |
Sequence similarities
Belongs to the ALAD family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length402
- Mass (Da)44,106
- Last updated2016-04-13 v1
- Checksum52B631F98E49E4F7
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 41-55 | Polar residues | ||||
Sequence: RSSEQASTSANSPLL |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP006486 EMBL· GenBank· DDBJ | BAM79178.1 EMBL· GenBank· DDBJ | Genomic DNA |