A0A120KW31 · A0A120KW31_9FUNG

  • Protein
    Leukotriene A(4) hydrolase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

162150100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site137-139a peptide (UniProtKB | ChEBI)
Binding site268-273a peptide (UniProtKB | ChEBI)
Binding site297Zn2+ (UniProtKB | ChEBI); catalytic
Active site298Proton acceptor
Binding site301Zn2+ (UniProtKB | ChEBI); catalytic
Binding site320Zn2+ (UniProtKB | ChEBI); catalytic
Active site386Proton donor
Binding site571-573a peptide (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionaminopeptidase activity
Molecular Functionepoxide hydrolase activity
Molecular Functionmetallopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leukotriene A(4) hydrolase
  • EC number
  • Short names
    LTA-4 hydrolase

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Mucoromycotina > Mucoromycetes > Mucorales > Mucorineae > Mucoraceae > Actinomucor

Accessions

  • Primary accession
    A0A120KW31

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain471-615Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    621
  • Mass (Da)
    70,201
  • Last updated
    2016-04-13 v1
  • Checksum
    5B1A0081B11C9D76
MCVSSATIDLSTQANIDEIKTTHVHLNWNVDFENQNLHGNVVLDLQTLVDNVDKVVLDTSYLDIKAVHFGDQVLKHQVAERYASLGSALTIQVPTVEKAGTNFQIKIDYATTENCTAVQFLKPEQTLGGKHPYLFSQSEPIHGRAMIPCQDSPSVKVTYSASVRSHLPVVMSALQTGVDEDADKEVGFKTYHFSQKTSIPSYLIAIAVGNLVGQEIGPRSTVWCEPEMIEQAAWEFSDTESFVATGEDLLTPYEWGRYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSAVNVIAHEISHSWMGNLVTTNAWKHYWLNEGWTVFIERKILGRLYGEATRQFEALSGLKSLQESVDLFGKDSLKTVLNPDLRNGADPDDFFSKVPYEKGFNFLYHIEKVVGGPSIFEPYMKAYVQRFASTSISTEDWKAFLFEYMEKTHGAEMVKKLNTIDFDTWINKPGMPPVDPEFDTSLADACYDLAKRWDEARHSDDLSFSAKDIENFSAGQKIVFLEKLTDSEPLPHHLVQKMDELYNFTSNHNADLRLRWQQVCLMTSYEPIYPEVVKFITEQGRMKFVRPLYRLLHQAKNGAQLAVDTYLEHKSFYHPIAAQLIEKDIGLVKSL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KP973592
EMBL· GenBank· DDBJ
AME15515.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp