A0A120A0W8 · A0A120A0W8_9BACE
- ProteinL-aspartate dehydrogenase
- GenenadX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids263 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Miscellaneous
The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.
Catalytic activity
- H2O + L-aspartate + NAD+ = H+ + NADH + NH4+ + oxaloacetate
Pathway
Cofactor biosynthesis; NAD+ biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | |
Biological Process | NAD biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-aspartate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionA0A120A0W8
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-125 | Aspartate/homoserine dehydrogenase NAD-binding | ||||
Sequence: GCGRLAGIVSDAVVNGLLPEYDLVGVYSRTAEKAERIVSKMQQHGKSCVACTTPEDLLALKPDYLVEAASPAAMKEFALPALKNGTSIVTLSIGALADTAFYQEVMETAKANGTRVYI | ||||||
Domain | 170-241 | Aspartate dehydrogenase | ||||
Sequence: TEQRVVFSGNATEAIAMFPTKVNVAVAASLASIGPENMEMSMQSTPGFVGDTQRVEIKNDQVHAVIDVYSAT |
Sequence similarities
Belongs to the L-aspartate dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length263
- Mass (Da)27,879
- Last updated2016-04-13 v1
- ChecksumFF8B10A35402C7D6