A0A109UV21 · A0A109UV21_9EURY
- ProteinTetrahydromethanopterin S-methyltransferase subunit A
- GenemtrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids186 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
Catalytic activity
- 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na+(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na+(out)
Cofactor
Note: Binds 1 5-hydroxybenzimidazolylcobamide group.
Pathway
One-carbon metabolism; methanogenesis from CO2; methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 82 | 5-hydroxybenzimidazolylcob(I)amide (UniProtKB | ChEBI); cofactor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | cobalt ion binding | |
Molecular Function | tetrahydromethanopterin S-methyltransferase activity | |
Biological Process | methanogenesis, from carbon dioxide | |
Biological Process | methylation | |
Biological Process | one-carbon metabolic process | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTetrahydromethanopterin S-methyltransferase subunit A
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobrevibacter
Accessions
- Primary accessionA0A109UV21
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Keywords
- Cellular component
Interaction
Subunit
The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length186
- Mass (Da)19,873
- Last updated2016-04-13 v1
- Checksum6D04A4DA5AB492FA
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP010834 EMBL· GenBank· DDBJ | AMD18065.1 EMBL· GenBank· DDBJ | Genomic DNA |