A0A109UV21 · A0A109UV21_9EURY

  • Protein
    Tetrahydromethanopterin S-methyltransferase subunit A
  • Gene
    mtrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.

Catalytic activity

Cofactor

5-hydroxybenzimidazolylcob(I)amide (UniProtKB | Rhea| CHEBI:60494 )

Note: Binds 1 5-hydroxybenzimidazolylcobamide group.

Pathway

One-carbon metabolism; methanogenesis from CO2; methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site825-hydroxybenzimidazolylcob(I)amide (UniProtKB | ChEBI); cofactor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncobalt ion binding
Molecular Functiontetrahydromethanopterin S-methyltransferase activity
Biological Processmethanogenesis, from carbon dioxide
Biological Processmethylation
Biological Processone-carbon metabolic process
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tetrahydromethanopterin S-methyltransferase subunit A
  • EC number
  • Alternative names
    • N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Gene names

    • Name
      mtrA
    • ORF names
      TL18_08555

Organism names

  • Taxonomic identifier
  • Strain
    • YE315
  • Taxonomic lineage
    Archaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobrevibacter

Accessions

  • Primary accession
    A0A109UV21

Proteomes

Subcellular Location

Cell membrane
; Single-pass membrane protein

Keywords

Interaction

Subunit

The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the MtrA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    186
  • Mass (Da)
    19,873
  • Last updated
    2016-04-13 v1
  • Checksum
    6D04A4DA5AB492FA
MADKKAPADGWPVISGDYIVGDPESPVAVTTLASHIEAELSGAAIAGPCKTENLGIEKVVANIISNPNIRFLILAGAEVQGHITGQSIQALYDNGADPDKKKIIGATGAIPFVENVPLEGIERFQQQLEIVDLIDTEDIGAIQSKINECVEKDPGALEEDPIVMEVDEENEKMVIVDQEAEEEAED

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP010834
EMBL· GenBank· DDBJ
AMD18065.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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