A0A108T267 · A0A108T267_9BACE

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site75Na+ (UniProtKB | ChEBI); structural
Binding site78Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      crcB
    • Synonyms
      fluC
    • ORF names
      F2Y81_26635

Organism names

  • Taxonomic identifier
  • Strain
    • BIOML-A6
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides

Accessions

  • Primary accession
    A0A108T267

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane34-55Helical
Transmembrane67-83Helical
Transmembrane95-116Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    131
  • Mass (Da)
    14,283
  • Last updated
    2016-04-13 v1
  • Checksum
    F20E9B652CDA12BA
MKELIYIFLGGGTGSVLRYYVQELLHERIIPYSFPWATFTVNIFGSFLIGLFYALSTRFNLSPEMRLLLTAGFCGGFTTFSTFSNDGLTLLKGGFYGTFIAYTLISITLGILAALAGGAVGTNHLSLTTNH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VVYV01000078
EMBL· GenBank· DDBJ
KAA5412186.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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