A0A106RSA3 · A0A106RSA3_BURCE

Function

function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 2 iron ions per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site144Fe cation 1 (UniProtKB | ChEBI)
Binding site175Fe cation 2 (UniProtKB | ChEBI)
Binding site175Fe cation 1 (UniProtKB | ChEBI)
Binding site178Fe cation 1 (UniProtKB | ChEBI)
Active site182
Binding site248Fe cation 2 (UniProtKB | ChEBI)
Binding site282Fe cation 2 (UniProtKB | ChEBI)
Binding site285Fe cation 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Biological Processdeoxyribonucleotide biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonucleoside-diphosphate reductase subunit beta
  • EC number

Gene names

    • Name
      nrdB
    • ORF names
      E3D37_24690
      , JAO13_24615
      , NCTC10661_05246

Organism names

  • Taxonomic identifier
  • Strains
    • 871
    • NCTC10661
    • d13
    • D13
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A106RSA3
  • Secondary accessions
    • A0A1I0IBG8

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane240-262Helical

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-22Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    403
  • Mass (Da)
    45,941
  • Last updated
    2016-04-13 v1
  • Checksum
    C3106348072494A9
MLNWDDEKTAVTPASGAQQNAMRTSAGMAVGMQAATPAAHQVRDIFEGDLAVPPQASAVPAGGSEARVNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVTSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAEFRAEIRELFKQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFISNRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAEDXG010000025
EMBL· GenBank· DDBJ
MBH9699633.1
EMBL· GenBank· DDBJ
Genomic DNA
UARD01000034
EMBL· GenBank· DDBJ
SQA54393.1
EMBL· GenBank· DDBJ
Genomic DNA
SNSQ01000031
EMBL· GenBank· DDBJ
TEU42513.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp