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A0A104K4R4 · A0A104K4R4_9BURK

  • Protein
    NADH-quinone oxidoreductase subunit I
  • Gene
    nuoI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters per subunit.

Features

Showing features for binding site.

116220406080100120140160
TypeIDPosition(s)Description
Binding site63[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site66[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site69[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site73[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site102[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site105[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site108[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site112[4Fe-4S] cluster 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit I
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit I
    • NDH-1 subunit I

Gene names

    • Name
      nuoI
    • ORF names
      BW685_08680
      , DF011_23510
      , WI38_13525
      , WJ33_01380
      , WJ35_00860
      , WJ96_17945
      , WK53_00580
      , WK55_19165
      , WK57_11670
      , WK67_15590
      , WL19_12345
      , WL29_03125
      , WL73_20995
      , WM16_02295

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • MSMB1137WGS
    • MSMB1140WGS
    • MSMB1608WGS
    • MSMB1808WGS
    • MSMB2036
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A104K4R4

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain54-834Fe-4S ferredoxin-type
Domain93-1224Fe-4S ferredoxin-type

Sequence similarities

Belongs to the complex I 23 kDa subunit family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    162
  • Mass (Da)
    18,672
  • Last updated
    2016-04-13 v1
  • MD5 Checksum
    9BE0B2EEECA14FE70AFF916013B89076
MTAIQHFFKTFFLTELLKGLALTGRYAFRRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPAMAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPYR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP013420
EMBL· GenBank· DDBJ
AOJ73783.1
EMBL· GenBank· DDBJ
Genomic DNA
CP013446
EMBL· GenBank· DDBJ
AOK24027.1
EMBL· GenBank· DDBJ
Genomic DNA
LOTN01000027
EMBL· GenBank· DDBJ
KUZ90525.1
EMBL· GenBank· DDBJ
Genomic DNA
LOXM01000264
EMBL· GenBank· DDBJ
KVG54946.1
EMBL· GenBank· DDBJ
Genomic DNA
LPBJ01000092
EMBL· GenBank· DDBJ
KVP90350.1
EMBL· GenBank· DDBJ
Genomic DNA
LPDO01000091
EMBL· GenBank· DDBJ
KVT51128.1
EMBL· GenBank· DDBJ
Genomic DNA
LPDQ01000095
EMBL· GenBank· DDBJ
KVT54642.1
EMBL· GenBank· DDBJ
Genomic DNA
LPGK01000147
EMBL· GenBank· DDBJ
KVZ51471.1
EMBL· GenBank· DDBJ
Genomic DNA
LPHD01000187
EMBL· GenBank· DDBJ
KWA73734.1
EMBL· GenBank· DDBJ
Genomic DNA
LPIX01000079
EMBL· GenBank· DDBJ
KWD98038.1
EMBL· GenBank· DDBJ
Genomic DNA
LPLU01000012
EMBL· GenBank· DDBJ
KWK84587.1
EMBL· GenBank· DDBJ
Genomic DNA
LNJU01000001
EMBL· GenBank· DDBJ
KWZ61150.1
EMBL· GenBank· DDBJ
Genomic DNA
MTJZ01000008
EMBL· GenBank· DDBJ
OMG74077.1
EMBL· GenBank· DDBJ
Genomic DNA
QTOC01000020
EMBL· GenBank· DDBJ
RQQ07926.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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