A0A101FL26 · A0A101FL26_9BACT
- ProteinAnthranilate phosphoribosyltransferase
- GenetrpD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids343 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
Catalytic activity
- N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate
Cofactor
Note: Binds 2 magnesium ions per monomer.
Pathway
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 80 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 80 | anthranilate 1 (UniProtKB | ChEBI) | |||
Binding site | 83-84 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 88 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 90-93 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 92 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 108-116 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 111 | anthranilate 1 (UniProtKB | ChEBI) | |||
Binding site | 120 | 5-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI) | |||
Binding site | 166 | anthranilate 2 (UniProtKB | ChEBI) | |||
Binding site | 225 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 226 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 226 | Mg2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | anthranilate phosphoribosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | tryptophan biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAnthranilate phosphoribosyltransferase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Synergistota > Synergistia > Synergistales
Accessions
- Primary accessionA0A101FL26
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-65 | Glycosyl transferase family 3 N-terminal | |||
Domain | 74-324 | Glycosyl transferase family 3 | |||
Sequence similarities
Belongs to the anthranilate phosphoribosyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length343
- Mass (Da)36,252
- Last updated2016-04-13 v1
- MD5 Checksum4A3641C19059FC72B558BF79F707260C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LGFQ01000086 EMBL· GenBank· DDBJ | KUK38992.1 EMBL· GenBank· DDBJ | Genomic DNA |