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A0A101CUV0 · A0A101CUV0_9FLAO

Function

function

Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    EC:2.7.13.3 (UniProtKB | ENZYME | Rhea)

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular Functionphosphorelay sensor kinase activity
Molecular Functionprotein dimerization activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Oxygen sensor histidine kinase NreB
  • EC number
  • Alternative names
    • Nitrogen regulation protein B

Gene names

    • ORF names
      AR687_04610

Organism names

Accessions

  • Primary accession
    A0A101CUV0

Proteomes

Subcellular Location

Cytoplasm
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-42Helical
Transmembrane193-211Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain323-374PAC
Domain509-600Histidine kinase

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    600
  • Mass (Da)
    69,548
  • Last updated
    2016-04-13 v1
  • MD5 Checksum
    27EDD83E3F48030CD522A5651AC2905D
MKKSNQEKDKITFKNLRRLYFFALLTIAFTIIVSQILVQYNLNQQLSDSKIINFSGKQRMLSQKIVKEVLILHYVSDTASSKQISHLKSVLWLWKKNQNALENGNDSLAFPKEKSETLYKLYQEINPIFYKIAQTTDSFLLNLKQKKQSDENQKFVNTILENEGAFLSKMNQIVTQYDLEAHEKVTEQRKIEYWIFGFTLLVLLLEFFFIFKPTNKKIERLITRLLASEKKALKLAYDTEIISEIKENSVKELKSLNYAMENTLLYCRIAPDGSIIHIGEKFAKLINYTKFSSNKKFSEVLTTDEKEQLNIDRIIFEKHRSGWQGEIKIINKENQTIWLDLSMVPVTIKKDELELLIVCFNITERKKAQREVERLNIENSTEKINQQKIISSKIVENQENEQNRIAKEIHDGIGQMLTGLKFSLESINLDDREKSAQKIEYLKKLSLDIIKGVRTATFNLMPPELSDHGIVSSLAKLTQELSKLTGKEILFYNKTDFNQRLDSLIEINIYRLTQEAINNAIKYAESSHIIVQLSHSSTLLSIIVDDNGKGFDISAVDKKRNSESGMGMLFMKERIQYINGRVFFKSIPGEGTRITFNIPI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LMAJ01000004
EMBL· GenBank· DDBJ
KUJ62690.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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