A0A101CR11 · A0A101CR11_9FLAO
- Protein3'-phosphate/5'-hydroxy nucleic acid ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids473 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 147 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 227-231 | GMP (UniProtKB | ChEBI) | |||
Binding site | 228 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 257 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 339 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 339-340 | GMP (UniProtKB | ChEBI) | |||
Binding site | 371-374 | GMP (UniProtKB | ChEBI) | |||
Active site | 395 | GMP-histidine intermediate | |||
Binding site | 395-398 | GMP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA ligase activity | |
Molecular Function | GTP binding | |
Molecular Function | manganese ion binding | |
Molecular Function | RNA ligase (GTP) activity | |
Biological Process | DNA repair | |
Biological Process | RNA processing | |
Biological Process | RNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3'-phosphate/5'-hydroxy nucleic acid ligase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae
Accessions
- Primary accessionA0A101CR11
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length473
- Mass (Da)51,620
- Last updated2016-04-13 v1
- MD5 ChecksumBD0314FAB3D8972AB9FA999B9E993FEA
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LMAJ01000017 EMBL· GenBank· DDBJ | KUJ60682.1 EMBL· GenBank· DDBJ | Genomic DNA |