A0A0X1KG70 · ORM2B_HUMAN
- ProteinOlfactory receptor 4M2
- GeneOR4M2B
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids313 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Odorant receptor.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | olfactory receptor activity |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameOlfactory receptor 4M2
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A0X1KG70
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-25 | Cytoplasmic | ||||
Sequence: METANYTKVTEFVLTGLSQTPEVQL | ||||||
Transmembrane | 26-46 | Helical; Name=1 | ||||
Sequence: VLFVIFLSFYLFILPGNILII | ||||||
Topological domain | 47-57 | Extracellular | ||||
Sequence: CTISLDPHLTS | ||||||
Transmembrane | 58-78 | Helical; Name=2 | ||||
Sequence: PMYFLLANLAFLDIWYSSITA | ||||||
Topological domain | 79-97 | Cytoplasmic | ||||
Sequence: PEMLIDFFVERKIISFDEC | ||||||
Transmembrane | 98-118 | Helical; Name=3 | ||||
Sequence: IAQLFFLHFAGASEMFLLTVM | ||||||
Topological domain | 119-142 | Extracellular | ||||
Sequence: AFDLYTAICRPLHYATIMNQRLCC | ||||||
Transmembrane | 143-163 | Helical; Name=4 | ||||
Sequence: ILVALSWRGGFIHSIIQVALI | ||||||
Topological domain | 164-204 | Cytoplasmic | ||||
Sequence: VRLPFCGPNELDSYFCDITQVVRIACANTFPEELVMICSSG | ||||||
Transmembrane | 205-225 | Helical; Name=5 | ||||
Sequence: LISVVCLIALLMSYAFLLALL | ||||||
Topological domain | 226-238 | Extracellular | ||||
Sequence: KKLSGSGENTNRA | ||||||
Transmembrane | 239-259 | Helical; Name=6 | ||||
Sequence: VSTCYSHITIVVLMFGPSIYI | ||||||
Topological domain | 260-270 | Cytoplasmic | ||||
Sequence: YARPFDSFSLD | ||||||
Transmembrane | 271-291 | Helical; Name=7 | ||||
Sequence: KVVSVFNTLIFPLHNPIIYTL | ||||||
Topological domain | 292-313 | Extracellular | ||||
Sequence: RNKEVKAAMRKLVTKYILCKEK |
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 487 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000451613 | 1-313 | Olfactory receptor 4M2 | |||
Sequence: METANYTKVTEFVLTGLSQTPEVQLVLFVIFLSFYLFILPGNILIICTISLDPHLTSPMYFLLANLAFLDIWYSSITAPEMLIDFFVERKIISFDECIAQLFFLHFAGASEMFLLTVMAFDLYTAICRPLHYATIMNQRLCCILVALSWRGGFIHSIIQVALIVRLPFCGPNELDSYFCDITQVVRIACANTFPEELVMICSSGLISVVCLIALLMSYAFLLALLKKLSGSGENTNRAVSTCYSHITIVVLMFGPSIYIYARPFDSFSLDKVVSVFNTLIFPLHNPIIYTLRNKEVKAAMRKLVTKYILCKEK | ||||||
Disulfide bond | 97↔179 | |||||
Sequence: CIAQLFFLHFAGASEMFLLTVMAFDLYTAICRPLHYATIMNQRLCCILVALSWRGGFIHSIIQVALIVRLPFCGPNELDSYFC |
Keywords
- PTM
Proteomic databases
Interaction
Miscellaneous
Structure
Sequence
- Sequence statusComplete
- Length313
- Mass (Da)35,403
- Last updated2016-03-16 v1
- ChecksumA0D788C8FBB5F569
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0G2JMP0 | A0A0G2JMP0_HUMAN | OR4M2B | 313 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC135068 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |