A0A0W4ZIF1 · A0A0W4ZIF1_PNEC8
- ProteinGlyceraldehyde-3-phosphate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids340 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- D-glyceraldehyde 3-phosphate + phosphate + NAD+ = (2R)-3-phospho-glyceroyl phosphate + NADH + H+
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 13-14 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 35 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 80 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 122 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 151-153 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | |||
Active site | 152 | Nucleophile | |||
Site | 179 | Activates thiol group during catalysis | |||
Binding site | 182 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 211-212 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 234 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 316 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlyceraldehyde-3-phosphate dehydrogenase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Taphrinomycotina > Pneumocystomycetes > Pneumocystaceae > Pneumocystis
Accessions
- Primary accessionA0A0W4ZIF1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-152 | Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding | |||
Sequence similarities
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length340
- Mass (Da)36,576
- Last updated2016-03-16 v1
- Checksum8790A0B5FBC9D0AB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LFVZ01000008 EMBL· GenBank· DDBJ | KTW28160.1 EMBL· GenBank· DDBJ | Genomic DNA |