A0A0W4ZBF5 · A0A0W4ZBF5_PNEC8
- Protein2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- GeneCOQ5
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Catalytic activity
- a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H+ + S-adenosyl-L-homocysteine
a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10858 + CHEBI:59789 = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10859 + CHEBI:15378 + CHEBI:57856
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extrinsic component of mitochondrial inner membrane | |
Molecular Function | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Taphrinomycotina > Pneumocystomycetes > Pneumocystaceae > Pneumocystis
Accessions
- Primary accessionA0A0W4ZBF5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
Structure
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)33,984
- Last updated2016-03-16 v1
- ChecksumFB23BA104B22E2D0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LFVZ01000016 EMBL· GenBank· DDBJ | KTW25746.1 EMBL· GenBank· DDBJ | Genomic DNA |