A0A0W0DKL4 · A0A0W0DKL4_CANGB

Function

Miscellaneous

The active site is a redox-active disulfide bond.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site70FAD (UniProtKB | ChEBI)
Binding site135FAD (UniProtKB | ChEBI)
Binding site170-172FAD (UniProtKB | ChEBI)
Binding site207-214NAD+ (UniProtKB | ChEBI)
Binding site230NAD+ (UniProtKB | ChEBI)
Binding site299NAD+ (UniProtKB | ChEBI)
Binding site340FAD (UniProtKB | ChEBI)
Binding site346-349FAD (UniProtKB | ChEBI)
Active site472Proton acceptor

GO annotations

AspectTerm
Cellular Componentglycine cleavage complex
Cellular Componentmitochondrial nucleoid
Cellular Componentoxoglutarate dehydrogenase complex
Cellular Componentpyruvate dehydrogenase complex
Molecular Functiondihydrolipoyl dehydrogenase activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglycine dehydrogenase (decarboxylating) activity
Molecular Functionoxoglutarate dehydrogenase (succinyl-transferring) activity
Molecular Functionpyruvate dehydrogenase activity
Biological Process2-oxoglutarate metabolic process
Biological Processglycine catabolic process
Biological Processhydrogen peroxide metabolic process
Biological Processisoleucine catabolic process
Biological ProcessL-leucine catabolic process
Biological ProcessL-serine biosynthetic process
Biological Processpyruvate metabolic process
Biological Processvaline catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihydrolipoyl dehydrogenase
  • EC number

Gene names

    • ORF names
      AO440_001183

Organism names

Accessions

  • Primary accession
    A0A0W0DKL4

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond61↔66Redox-active

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-355FAD/NAD(P)-binding
Domain374-482Pyridine nucleotide-disulphide oxidoreductase dimerisation

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    493
  • Mass (Da)
    53,148
  • Last updated
    2016-03-16 v1
  • Checksum
    35C80187F2CD98E3
MFRAVSRRGFSSSSYLAAIKKQHDLVIIGGGPGGYVAAIKAAQLGLDTACIEKRGSLGGTCLNVGCIPSKALLNNSHLYHQIKSDTKNRGIDVKGEVEINVEQFQKAKDTVVKQLTGGVEMLFKKYKVNYYKGVGSFESENSVKVTPVEGIKGTVEDETIIEAKNIIIATGSEVTPFPGIKIDEERIVSSTGALSLKEVPKRLAVIGGGIIGLEMGSVYSRLGSKVTVLEFQPKIGASMDGEVAATSQKFLKKQGFNFKLSTKVVSAERNGDVVDIVVEDTKSGKTENIQADVLLVAVGRRPYIEGLGAEKLGLEVDKRGRLVIDEQFSTKHPHIKVIGDVTFGPMLAHKAEEEGIAAVEYIKKGHGHVNYGNIPSVMYTHPEVAWVGKTEEQLTEEGIKYKVGKFPFIANSRAKTNMETEGFVKILIDAETERMLGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANLAAFDKPINF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LLZZ01000022
EMBL· GenBank· DDBJ
KTB12344.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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