A0A0W0C789 · A0A0W0C789_CANGB
- ProteinBis(5'-adenosyl)-triphosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids190 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.
Catalytic activity
- P1,P3-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H+
Cofactor
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 30 | substrate | |||
Binding site | 87 | substrate | |||
Binding site | 93-96 | substrate | |||
Active site | 100 | Tele-AMP-histidine intermediate | |||
Binding site | 102 | substrate | |||
Site | 117 | Important for induction of apoptosis | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | bis(5'-adenosyl)-triphosphatase activity | |
Molecular Function | nucleotide binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBis(5'-adenosyl)-triphosphatase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Nakaseomyces
Accessions
- Primary accessionA0A0W0C789
Proteomes
Organism-specific databases
Structure
Sequence
- Sequence statusComplete
- Length190
- Mass (Da)22,284
- Last updated2016-03-16 v1
- Checksum6123A27F85AD2162
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LLZZ01000107 EMBL· GenBank· DDBJ | KTB07688.1 EMBL· GenBank· DDBJ | Genomic DNA |