A0A0V0PU86 · A0A0V0PU86_9RHOB

  • Protein
    Triosephosphate isomerase
  • Gene
    tpiA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Carbohydrate metabolism; erythritol degradation.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site10-12substrate
Active site90Electrophile
Active site160Proton acceptor
Binding site166substrate
Binding site204substrate
Binding site225-226substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA
    • ORF names
      AQY21_25145

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MKU1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Paracoccus

Accessions

  • Primary accession
    A0A0V0PU86

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    24,545
  • Last updated
    2016-03-16 v1
  • Checksum
    C9BA8197D19E4C4B
MAPRKLAAGNWKMNGTLASLAEIDRLLADHPASGCDVLICPPATLIQAMAAKGIATGGQDCHAKASGAHTGDIAAQQLKDVGASHVILGHSERRTDHGETDAQVAAKSVAAHEAGLVAVICVGETEAQRDAGETLDVIAAQLAGSVPDGATAANTVIAYEPVWAIGTGRTPTSDQIAEVHALMHERLSARFADGADMALLYGGSVKPGNAAEVFAIPHVNGALVGGASLKAADFGPIIAALSAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LLWQ01000220
EMBL· GenBank· DDBJ
KRW93457.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp