A0A0U1MB98 · A0A0U1MB98_TALIS

Function

Catalytic activity

Pathway

Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functiontetrahydrofolylpolyglutamate synthase activity
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tetrahydrofolate synthase
  • EC number
  • Alternative names
    • Folylpoly-gamma-glutamate synthetase
    • Tetrahydrofolylpolyglutamate synthase

Gene names

    • Name
      FPGS
    • ORF names
      PISL3812_09931

Organism names

  • Taxonomic identifier
  • Strain
    • WF-38-12
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Islandici

Accessions

  • Primary accession
    A0A0U1MB98

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-28Disordered
Compositional bias10-28Basic and acidic residues
Compositional bias261-279Polar residues
Region261-337Disordered
Compositional bias289-337Polar residues
Region377-414Disordered
Domain1519-1689JmjC
Region1738-1765Disordered
Compositional bias1741-1759Basic and acidic residues

Sequence similarities

Belongs to the folylpolyglutamate synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,790
  • Mass (Da)
    201,469
  • Last updated
    2016-02-17 v1
  • Checksum
    FD79C237E043BFF1
MSLYNFRDYGTGDTRKRIRGEHNHTDSTRKRLGSAVLNTGGHGPVADESRREHTTVVEPQATNPSANRHTVEVDRRCDTDEQMAYALTSLSRCAQANNRVSIQDHNVNEIPPEIHVYRGMPTDTSHLDGARLNAFEGNPSNQMQEAASGQSRSYNPSIHVRVPLRVQAPFQESYNSRDVRTAVGGMGSRTGNELHHRTHQPRAICSNTSSQDCLEIPPPYTLDPVPTAKLYNTSFTIVHDNSPDPTQGVPGTETTQHLDVSQVRVSASDSQQGPVSSREDPQVPPSPCSPTTTGTQQSERIGNNTRVSSPSSVSPQLSPDTMQPAASPGIHNDTDNVDTTQALSATPVLCDSNSLPTSLSRPINDSRLIIHHSQCTESSLQNGARNSTLEPSHFRSGWQVAPSTEPYTNPQLSNDPSSNIVSIVPRIVLDSQQLPLTDTSRDMAALLCLLHSSTVSMELFNRARSPYRFWGSDGEISQGTVSICKMVEDISIFQQSLNELQKWGGVTVTRDAQSILLHESLSQLASNNTRWKLEAVKIVFAAFPVDRRVEPARSFSIATSLLPYLRAVRPLIREIHIDESLTPVHVIDVCLSASEYSDMQWKDECITTARSVAEDYQVGHIYRQRISLREMKLSRLRSKWGCDIDFKQFEYLNIYTEDPRSNAYHGGQLLLLSELFLEASDTNAALETLASYKYWDDERPSTMEKSQRYQVKVQQGKILQFSGRFKAAESHLLESLAWNQQETTTPIQATIHLVGVYCELGDPNRGIRLAENDLKCMLNQNTTRPNTRIVKKLKLSLAYAYLLDVMWNFLRPVRCNAHSLDHARDLFKDLRDSFTDNPSRANKINQVSLLLGLAAVAHLKGLYLDALSYYDDVLEAAKQCGWRIGYIESVVNASKSVVQYRLGRFRDAEQSDEIARGLYSSRSYFLVGFGTLWPEIIGTCPLTSVKTLIKELNGLRRGPRPETRVTSEKCVRGKPATAGMDKWIKSLGYSFDDINALNVIHVAGTKGKGSTCAFTECILRQHGLKTGLYTSPHLNTVRERIQINAQPLNENKFAEYAWFVFESLGLQKRQSDGPRYLQFLTLVSFHAFIKERVDVAIYETHQGGEYDSTNVITEPIVTAITSLGRDHIHQLGPTLEDVAWHKAGIFKRGAAALSVPHEPTLASVLEARAEEKGANLRFVDIGDNVPKDVSMPKYRVQQLNFSLAWAICNAFVKKKGTGLISSHNLKLALNDYSWRGRLQQISDGNITWFLDGAHNGISLPVCAEWFASASKEWEPDSSVDRVLIFSHYSTHRDGLELLTILGNSLSNRAIYIRQALFTRCEYENNDPQTRLLEDYKRIWTENYGKSDEVKTSETAFDAFASLEAAKKSKRLRRELDDELSIQWGEYDINIPTRDTPGIEEIRDFLQDLEKQSSYPQIIPVNCIPMHKLEIIQHLYNDLPKNDIIFTRQLGKIDKVLGGPFDKPVLYRPKHHQYDLDIEGFLEWFSKNKKSALHVYDYSITDASQRTRDTTVEEALHSFPSRPDANPLNFLDIENRTGAFYCPAQITQHDIQTRVAHQRQENVGKIGSTWIWKKPSEFFLLSTRHAVSSIHIDNGGQLTWIRVLEGRKIWYFPRSLNMKTLRWLAMAGSQSPEHYRDGWVKVELCAGDILVMPPGCPHAVFTPDDCLAVGGQFWTTAHLGRTLEVLQMQETHPDICNEDIDDTIYETLGEILQTCDSVMTPVEIAEVIANSYLFIGDHDDSSASSQKSHRGRELRSSRKEQSVQQDIPLSRRRFIQGLKKFTTTHQGVIEG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias10-28Basic and acidic residues
Compositional bias261-279Polar residues
Compositional bias289-337Polar residues
Compositional bias1741-1759Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CVMT01000022
EMBL· GenBank· DDBJ
CRG92858.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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