A0A0T7EWF2 · A0A0T7EWF2_9VIBR

  • Protein
    Guanosine-inosine kinase
  • Gene
    gsk
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Purine metabolism; GMP biosynthesis via salvage pathway.
Purine metabolism; IMP biosynthesis via salvage pathway; IMP from inosine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site40-45GMP (UniProtKB | ChEBI)
Binding site93-97GMP (UniProtKB | ChEBI)
Binding site198GMP (UniProtKB | ChEBI)
Binding site284-289ATP (UniProtKB | ChEBI)
Binding site357ATP (UniProtKB | ChEBI)
Binding site402ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionguanosine kinase activity
Molecular Functioninosine kinase activity
Biological ProcessGMP salvage
Biological ProcessIMP salvage
Biological Processpurine ribonucleoside salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Guanosine-inosine kinase
  • EC number

Gene names

    • Name
      gsk
    • ORF names
      FHG74_21880
      , JOS67_09475
      , OWD07_10490
      , VDIAB_270621

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • CNCM I-1629
    • CAIM 1802
    • SLV18
    • LCU-VD32
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio > Vibrio diabolicus subgroup

Accessions

  • Primary accession
    A0A0T7EWF2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain77-291Carbohydrate kinase PfkB

Sequence similarities

Belongs to the carbohydrate kinase PfkB family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    434
  • Mass (Da)
    48,487
  • Last updated
    2016-02-17 v1
  • Checksum
    D0871DA4C258EF9B
MKFPGQRKSKHYFPVHARDPLVSQAQESKKMTRTHIIGIDQTLVDIEAKVTTDVIEKYGLSKGHSLVIDDERAEELYQQLKEENLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDGERTFAISEGQMNQLHPDSIPEKIFKNASALVLTSYLVRCKEGDPMPEATMKAIEYAKKNDVPVVLTLGTKFVIQDDPKYWQEFIRDNVSVVAMNEDEAEALTGESDPLAASDKTLEWADLVLCTAGPVGLFMAGYTEDSAKRETSLPLLPGSIAEFNRYEFSRPAKKDTCETPIKVYSHISPYMGGPEKIKNTNGAGDAALSAVLHDMAANKYHKENVPNSSKHSNEYLTYSSFSQVCKYANRASYEVLVQHSPRLSRGLPEREDSLEEAYWER

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CCKK01000020
EMBL· GenBank· DDBJ
CDU09969.1
EMBL· GenBank· DDBJ
Genomic DNA
JAPSFE010000003
EMBL· GenBank· DDBJ
MCZ0740909.1
EMBL· GenBank· DDBJ
Genomic DNA
CP069195
EMBL· GenBank· DDBJ
QRG81841.1
EMBL· GenBank· DDBJ
Genomic DNA
VDEN01000143
EMBL· GenBank· DDBJ
TNC03727.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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