A0A0T7BX15 · A0A0T7BX15_9CYAN

  • Protein
    Aconitate hydratase B
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Organic acid metabolism; propanoate degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site192substrate
Binding site235-237substrate
Binding site404-406substrate
Binding site488substrate
Binding site700[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site758[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site761[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site780substrate
Binding site785substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function2-methylisocitrate dehydratase activity
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaconitate hydratase activity
Molecular Functionmetal ion binding
Biological Processpropionate catabolic process, 2-methylcitrate cycle
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aconitate hydratase B
  • EC number
  • Alternative names
    • 2-methylisocitrate dehydratase

Gene names

    • ORF names
      IJ00_21065

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 336/3
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Calotrichaceae > Calothrix

Accessions

  • Primary accession
    A0A0T7BX15

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-157Aconitase B HEAT-like
Domain169-372Aconitase B swivel
Domain459-807Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha

Sequence similarities

Belongs to the aconitase/IPM isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    863
  • Mass (Da)
    93,293
  • Last updated
    2016-02-17 v1
  • Checksum
    98C94AE579A6DEA5
MLESYRQQVEERASLGIPPLPLDAKQTSELCELLKNPPRGEEQTLLQLLRDRIPPGVDPAAYVKAGFLTAIAKGEISSPLVSPIVAVELLGTMLGGYNVASLIELLKSQDSGIAAAAAKALSHITLVYDAYHDVIDLAASNSYAQQVVDAWANADWFTSRPNLPQSITVSVFKVPGETNTDDLSPAQHATTRPDIPLHALAMLETRQPGSLATISQLKQKGHPVAYVGDVVGTGSSRKSAINSVLWHMGNDIPFVPNKRAGGYILGGTIAPIFFNTAEDAGALPIQCDVTKMETGMVITIYPYKGEITNESGEIISTFQLKPDTILDEVRAGGRIPLLIGRTLTDKTRTALNLPPSTLFARPQPPQDTGKGYTLAQKMVGKACGLPGVRPGTSCEPIMTTVGSQDTTGPMTRDELKELACLGFSADLVMQSFCHTAAYPKPVDIKTHAELPDFIAQRGGVALRPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVRFRGELQPGITLRDIVNAIPYVAIQKGLLTVEKKNKKNIFAGKILEIEGLPDLKVEQAFELTDASAERSCAGCTIKLSVETVSEYISSNVSLLKNMVARGYADARTIMRRVAKMEEWLANPVLMEADKDAEYAEIIEIDLNEITEPIVAAPNDPDNIKLLSEVANDPVQEVFVGSCMTNIGHYRATAKVLEGAGKVNARLWIAPPTRMDETQLKKEGVYDIFVAANARTEMPGCSLCMGNQARVEDGTTVFSTSTRNFNNRMGKDAQVYLGSAELAAVCALLGRIPTVQEYLKIVGERIQPFAENLYRYLNFDQISGFEDEGRVISKEEEAKILEVSMK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP011382
EMBL· GenBank· DDBJ
AKG23433.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp