A0A0T7BTC4 · A0A0T7BTC4_9CYAN

  • Protein
    DNA-directed RNA polymerase subunit beta'
  • Gene
    rpoC2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 Zn2+ ion per subunit.

Features

Showing features for binding site.

113541002003004005006007008009001,0001,1001,2001,300
TypeIDPosition(s)Description
Binding site219Zn2+ (UniProtKB | ChEBI)
Binding site293Zn2+ (UniProtKB | ChEBI)
Binding site300Zn2+ (UniProtKB | ChEBI)
Binding site303Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC2
    • ORF names
      IJ00_14725

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 336/3
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Calotrichaceae > Calothrix

Accessions

  • Primary accession
    A0A0T7BTC4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain7-61RNA polymerase Rpb1
Domain90-168RNA polymerase Rpb1
Domain171-1205RNA polymerase Rpb1
Region1326-1354Disordered

Sequence similarities

Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,354
  • Mass (Da)
    147,467
  • Last updated
    2016-02-17 v1
  • Checksum
    D6F30951EEFF867A
MTNEKHIFRNRVVDKGQLRNLISWSFTNYGTARTAVMADKLKDLGFRYATRAGVSISVDDLMVPPSKRNLLDAAEAEIQATQERYQRGEITEVERFQKVIDTWNGTSEALKDEVVTHFKKTNPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIREFDCGTTRGIPLRAMTEGSKILIKLSTRLVGRVINVDVVHPETGELIAARNTPVCDDLAIAIEKAGVEEVVVRSPLTCEAARSVCQHCYGWSLAHAKMVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVAKQVRAEMDCVVKFPKRLRTRPFRTRHGEDALYIEMNGHITIEPTEAGKKAEDISVTQGSTLYITDSQKVKQGQLIAEVALGGRTTRVNTEKAVKDVASDLAGEVKFADVVAEQKTDRQGNTTTTAARGGLIWILGGEVYNLPPGAELVVKNGDRISSNGVLAETKLTTLHGGVVRLPEATPGKSTREIEIITASVVLDQATVTAQSTQGRNNYLVTTGNNQVFNLRATPGTKVQNGQVVAELIDDRYRTTTGGMLKFAGVEVQKKGKAKQGYEVVQGGTLLWIPEESHEVNKDISLLLVEDGQYVNAGDEVVKDIFCQNSGVVEVTQKNDILREVVIKPGELLMVDDPEAVMSKDNTFVQAGEELLGQTVTELRYIQYVETPEGPALISRPVVEFAVPTSPDVPSTTSVSQQTGRSIQMRAVQRLPYKDSERVKSVEGVELLRTQLVLEIEQEGEQDHNTSPLAADIELVPDTENSEVQRLQLVILESLILRRDITADATQGSTQTNLEVQDGDTIAPGAVVARTQILCKEGGIVRGVQKGSENVRRCLVLRQQDLVRKQANAQPRVKVGELIVAGTEILPGVFAEESGQVVEVKSPGTASTTEEGALATQNYSVTVRLGRPYRVSPGAVLQVEDGDLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEACLLAKRSGELKVVYGDGDEAIAAKIIESNGVVTDYTLGPGQNLIFPDGAHIDAGDTLTDGPSNPHEILETFFNLGSEDGIYACASHALQKVQTFLVNEVQSVYQSQGIDIADKHIEVIVRQMTNKVRVDDGGDTTMLPGELVELRQIEQVNEAMAITGGARAQYTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGYNTYDEPGIVDDYTDVMNSNVLDEVDDPLDMVLDDRTARNYNLEVAPIVEGNYGGSVKRSGSILDDDEDLIAGEVSDLIDEEDYDDDDGDDGDDDEDDFDDD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP011382
EMBL· GenBank· DDBJ
AKG22351.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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