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A0A0S7BY15 · A0A0S7BY15_9CHLR

  • Protein
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • Gene
    pdxS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

129020406080100120140160180200220240260280
Type
IDPosition(s)Description
Binding site22D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site79Schiff-base intermediate with D-ribose 5-phosphate
Binding site151D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site163D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site212D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site233-234D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • EC number
  • Short names
    PLP synthase subunit PdxS
  • Alternative names
    • Pdx1

Gene names

    • Name
      pdxS
    • ORF names
      ATC1_131624

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TC1
  • Taxonomic lineage
    Bacteria > Chloroflexota > Anaerolineae > Anaerolineales > Anaerolineaceae > Flexilinea

Accessions

  • Primary accession
    A0A0S7BY15

Proteomes

Interaction

Subunit

In the presence of PdxT, forms a dodecamer of heterodimers.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-210PdxS/SNZ N-terminal

Sequence similarities

Belongs to the PdxS/SNZ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    290
  • Mass (Da)
    31,617
  • Last updated
    2016-02-17 v1
  • MD5 Checksum
    8B07C25B69664D37947B9D63B89642E4
MNERYELNKNLAQMLKGGVIMDVTSPEQARIAENAGACAVMALERIPADIRAAGGVSRMSDPKMIKEIQHAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADDLFHIDKTKFNVPFVCGAKDLGEALRRISEGASMIRTKGEPGTGDIIQAVRHMRMMMSQIRQIQNQREDELFHTAKELQVSYELVQYVHENGKLPVVNFAAGGVATPADAALMMQLGAEGVFVGSGIFKSGNPAKRAEAIVKSVTNFNNPALIAQLSEDLGEAMVGINEQEIDLLMAERGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DF968181
EMBL· GenBank· DDBJ
GAP41632.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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