A0A0S6UBX4 · A0A0S6UBX4_CLOBO

Function

function

Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site7-10ATP (UniProtKB | ChEBI)
Binding site47substrate
Binding site74substrate
Binding site173-174ATP (UniProtKB | ChEBI)
Binding site179ATP (UniProtKB | ChEBI)
Binding site184ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaspartate kinase activity
Molecular FunctionATP binding
Biological Processhomoserine biosynthetic process
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartokinase
  • EC number

Gene names

    • ORF names
      CBO05C_3473

Organism names

Accessions

  • Primary accession
    A0A0S6UBX4

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain265-336ACT
Domain342-400ACT

Sequence similarities

Belongs to the aspartokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    400
  • Mass (Da)
    43,472
  • Last updated
    2016-02-17 v1
  • Checksum
    E308C0EF3CD2AE1E
MATIVQKYGGTSVATVEKIKNVAKSIVKRKKEGNDIVVVVSAMGHTTDNLINLAKDISNVPDKRELDALISTGEMVSSSLLSMAIKELGEDAISYTAYQINISTNGQHGKSLINDIDEKKIDKSLKEGKVVVVAGFQGINCDGNITTLGRGGSDTSAVAIAAKLNNAICEIYTDVDGIYSVDPRAYNKAKKLDYIDYEEMLELSSLGAQVMHSRSIELAEKYNIPIYVGLSNGNIKGTVIRGMNNMNMEIKSVTGLATSDDDVAITMEDINEDINIVADIFTKLAEKQINVDMISQTAPINSRISLSFTIPKEDLQDGMKIIKGYAPKDKIKIDENLTKFSIVGIGMKNTSGVAAKMLKIFSDNNIKIKMITTSEIRITCAINVEDKINAINLVAKEFNL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DF384213
EMBL· GenBank· DDBJ
GAE03783.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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