A0A0S6U9X5 · A0A0S6U9X5_CLOBO

Function

function

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionpenicillin binding
Molecular Functionpeptidoglycan glycosyltransferase activity
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Penicillin-binding protein 1A
  • EC number

Gene names

    • ORF names
      CBO05C_3212

Organism names

Accessions

  • Primary accession
    A0A0S6U9X5

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein
Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-39Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain65-248Glycosyl transferase family 51
Domain358-632Penicillin-binding protein transpeptidase
Region754-838Disordered
Compositional bias765-788Basic and acidic residues
Compositional bias789-824Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    838
  • Mass (Da)
    93,758
  • Last updated
    2016-02-17 v1
  • Checksum
    F023989AD88199CC
MGKKKKKRKSSAFKIILNVFLSIFLVAGVAFGGIVFAMIKTAPPLNVQQVLTFDEPSILYDDKGQYMDKVITNEQRIVVDYKNVPQNLKNAFVSIEDERFYKHSGVDIKRFTGVILINVTNKIKRSSKLQGASTLTQQLIKNTVLSSEVSIKRKVQEMYLSIQLEKELSKDQILGAYMNSIFLGGNALGVEAASKQYFNKSVKDLSLIECAFIAGVPQSPSVYYPYSSAAKKNPSIYLNRTKTVLYKMLDNGYITQNDYNKALKDLDNKKLAFAKPSAPNNKLDYEWFSIPAIEQVKKDLKAQYKYDDKQIHNLLVNGGLKIYTTMNKNLQDKTQNTINNSYYLNSYKSNGMIYPQASAVIMDYHNGEVKTIIGGRGNQPARSYNRAASYNYLRPAGSSIKPLTVYSAAIDSKKATAATGFEDSPIPDNIGRKYSSGEPYNPRNTPNIYYGYVNVREALMHSINVIAVKLVDRIGLNTSIQYAEKFGIPIDQHDRTSIAALSLGELHKGTNPLIMAQAYGVFGNNGTYTEAKLYTKVVDRTGKIILEPKTHTKKVLSQEAAFITYDMLQGPVSEGGTGPQANFGNMEVRGKTGTSSDMKNLWFCGLTPYYSAAVWIGNDNSSTVNGVYSSTAAKLWGDIMKEFHVNLPYKQVQKPASVVTANVDRISGKLPTQLSYRDPRGSTVYNEFFINGTIPTEYDDIHVETQINKLTGKLASKFTPSFLVESRVFLKRDYSPGVELLDQQWVLPYSIDEGVSLPPTVEKNNSNIKDKDKNKYKNKDKDKNTEPDKPNSNNNNSNNNSNNNNNSNNNNNNNNNNTKPPENNPDQNQEDKNNKNKR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias765-788Basic and acidic residues
Compositional bias789-824Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DF384213
EMBL· GenBank· DDBJ
GAE03522.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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