A0A0S1VVS0 · A0A0S1VVS0_LETCA
- ProteinProtocadherin-h
- GenePcdh-h
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1356 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Potential calcium-dependent cell-adhesion protein.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Cyclostomata > Hyperoartia > Petromyzontiformes > Petromyzontidae > Lethenteron
Accessions
- Primary accessionA0A0S1VVS0
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 820-841 | Helical | ||||
Sequence: IIAMVAGAMIVIILVIVVVLFL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-28 | |||||
Sequence: MREPTSQRLRPPPLLLLLLLLSLVPGRA | ||||||
Chain | PRO_5006591603 | 29-1356 | ||||
Sequence: DEVNYRVFEELPANKLIGNLARDLNLRSLGPGLTYKIVSKYEGSPLVRVRNDTGELFTTATRIDREQLCPDVADEEAGCYHEVQVVVLPNQYFRLIKVKILVEDINDNAPSFPSPVINLTIAENMPVGTRFSLQAAGDPDAGLNGIQRYALTDTGNAFTLEVIEGADGEKSPQLLIRGSLDRERKEVYEMKLKAEDGGDPPRSSTAILRVTVTDVNDNHPVFEQSQIEVKIPENTPIGTPVIQLRATDADLGLNAEVTYSYSGRVSSPARRLFQLDNLTGVITVRGPLDREDTALYRLIVLATDRGPNPVPATATVTVSVADVNDNAPSVAVHDIISPVDGVIHLTEAAPPNTPIALIEVSDPDLEQNGRVTCRIEGDVPFQLKPAYQNHENQFLLETSALLDFETKNEYSVRLVATDLGSPRMSSTATVVVRLRDENDNPPVFNPGVVEATAYENNAPGAQIVTLAAGDRDSGKNAQMHYYLGPDAPPAFRLNPSTGVLSVAEPLDREERNLYRFSVIARDNGAPSMHGNATVVIRVLDQNDNPPKFNNKEFNFFLSENLPRFGTVGVISVTDADEGKNALVTFSLVGNSDIFTINPVTGMIQSNISFDREQKPSYTFQVQAVDAGEPPKTSFAKVTIHIMDINDNAPTVLLPPSNASYRLVTPSTSPGTSVAEVMATDIDSGENAELSYSVVGGNPFNLFAIDQATGNITLTQKLLPAHQGLHRLVVRVNDAGFPESLYSIVLVNLFVNETVGNASYVQELITKSLKLPLDVDVIGDGLSQSDINRYTTIIAMVAGAMIVIILVIVVVLFLRCRGNRMKSGVCRSKENENWLSPSQQDKQSKNRKKKRKKKQQQQQSQVKTAPYSIVTIEEPKSDDPTYQTINETLEELEVDCRTIPRHNTFRPDRTSDSPDLAKHYRSTSPQMAVSPHAHTPPLSKNQNVIQELPADNTFVGLGGESTSKRSSTSSDHFSVSESSSQSGFRASVQKLTKQQQQQQQQQQQQQASRRVKFMLEDGGTRQECCDSSLQSVADSGLGDPEATTTTATTAAVSSGSGSSASTASMASTSAVAAGAGILGVAGTAVGPAGPGGVLAGGLSAAGAAKLPGSQLTAPLLADSHYERTTPDGCTGETDHHPENGPAVVPARAALQTPIVVAKDLPDVALPSMCSTCTPECQMYGHSDNCWMPAGGVGGEGPAKSGSPLSPLSSYPPPLHRPEWDRRDLVPNGSALFHHGGPSGGVVGVGAGGSGNGGGGGGGGGDAVGGVGKPSSTSNRQANSYYNAFYSNNYRRHNDFLNEAEEIPLARPQAYRPATISTMSSPDFNKELYL |
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 49-140 | Cadherin | ||||
Sequence: ARDLNLRSLGPGLTYKIVSKYEGSPLVRVRNDTGELFTTATRIDREQLCPDVADEEAGCYHEVQVVVLPNQYFRLIKVKILVEDINDNAPSF | ||||||
Domain | 141-250 | Cadherin | ||||
Sequence: PSPVINLTIAENMPVGTRFSLQAAGDPDAGLNGIQRYALTDTGNAFTLEVIEGADGEKSPQLLIRGSLDRERKEVYEMKLKAEDGGDPPRSSTAILRVTVTDVNDNHPVF | ||||||
Domain | 251-358 | Cadherin | ||||
Sequence: EQSQIEVKIPENTPIGTPVIQLRATDADLGLNAEVTYSYSGRVSSPARRLFQLDNLTGVITVRGPLDREDTALYRLIVLATDRGPNPVPATATVTVSVADVNDNAPSV | ||||||
Domain | 365-472 | Cadherin | ||||
Sequence: SPVDGVIHLTEAAPPNTPIALIEVSDPDLEQNGRVTCRIEGDVPFQLKPAYQNHENQFLLETSALLDFETKNEYSVRLVATDLGSPRMSSTATVVVRLRDENDNPPVF | ||||||
Domain | 473-576 | Cadherin | ||||
Sequence: NPGVVEATAYENNAPGAQIVTLAAGDRDSGKNAQMHYYLGPDAPPAFRLNPSTGVLSVAEPLDREERNLYRFSVIARDNGAPSMHGNATVVIRVLDQNDNPPKF | ||||||
Domain | 577-679 | Cadherin | ||||
Sequence: NNKEFNFFLSENLPRFGTVGVISVTDADEGKNALVTFSLVGNSDIFTINPVTGMIQSNISFDREQKPSYTFQVQAVDAGEPPKTSFAKVTIHIMDINDNAPTV | ||||||
Domain | 691-788 | Cadherin | ||||
Sequence: VTPSTSPGTSVAEVMATDIDSGENAELSYSVVGGNPFNLFAIDQATGNITLTQKLLPAHQGLHRLVVRVNDAGFPESLYSIVLVNLFVNETVGNASYV | ||||||
Region | 854-908 | Disordered | ||||
Sequence: RSKENENWLSPSQQDKQSKNRKKKRKKKQQQQQSQVKTAPYSIVTIEEPKSDDPT | ||||||
Compositional bias | 928-943 | Basic and acidic residues | ||||
Sequence: RHNTFRPDRTSDSPDL | ||||||
Region | 928-966 | Disordered | ||||
Sequence: RHNTFRPDRTSDSPDLAKHYRSTSPQMAVSPHAHTPPLS | ||||||
Compositional bias | 944-966 | Polar residues | ||||
Sequence: AKHYRSTSPQMAVSPHAHTPPLS | ||||||
Region | 980-1037 | Disordered | ||||
Sequence: TFVGLGGESTSKRSSTSSDHFSVSESSSQSGFRASVQKLTKQQQQQQQQQQQQQASRR | ||||||
Compositional bias | 983-1037 | Polar residues | ||||
Sequence: GLGGESTSKRSSTSSDHFSVSESSSQSGFRASVQKLTKQQQQQQQQQQQQQASRR | ||||||
Region | 1058-1089 | Disordered | ||||
Sequence: SVADSGLGDPEATTTTATTAAVSSGSGSSAST | ||||||
Region | 1222-1301 | Disordered | ||||
Sequence: EGPAKSGSPLSPLSSYPPPLHRPEWDRRDLVPNGSALFHHGGPSGGVVGVGAGGSGNGGGGGGGGGDAVGGVGKPSSTSN |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,356
- Mass (Da)145,433
- Last updated2016-02-17 v1
- ChecksumB19E471E3CAD079B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 928-943 | Basic and acidic residues | ||||
Sequence: RHNTFRPDRTSDSPDL | ||||||
Compositional bias | 944-966 | Polar residues | ||||
Sequence: AKHYRSTSPQMAVSPHAHTPPLS | ||||||
Compositional bias | 983-1037 | Polar residues | ||||
Sequence: GLGGESTSKRSSTSSDHFSVSESSSQSGFRASVQKLTKQQQQQQQQQQQQQASRR |